PDF(Pubmed)
Abstract：
BACKGROUND: Cognitive function is crucial during aging. This study assessed the cognitive function of European adults aged 50 and over in relation to handgrip strength and physical inactivity. Study Design: This was a cross-sectional survey.
METHODS: Data were collected from 41,395 adults from 27 European countries participating in the Survey of Health, Ageing, and Retirement in Europe (SHARE) during 2019-2020. Cognitive function was assessed based on five tests, and cognitive impairment was defined using 3+tests. Handgrip strength and physical inactivity were also correlated through the analysis of covariance using a complex study design.
RESULTS: The majority of participants were female (56.6%), with a mean age of 70.9 years, and 22.6% presented multimorbidity. Furthermore, 51.1% had a normal cognitive function, while 13.3% had cognitive impairment (The estimated population was 21,944,722). Moreover, cognitive impairment was more prevalent in females than in males (14.4% vs. 12.0%, P<0.001) in patients with no years of education (P<0.001) and origin from southern European countries (P<0.001). Additionally, participants with cognitive impairment had lower mean handgrip strength compared to those with cognitive impairment in 1-2 criteria or with normal cognitive function (29.3 vs. 33.4 and 35.1 kg, respectively, P<0.001). Physically inactive participants had higher odds ratio (OR) of cognitive impairment than those engaging in moderate/vigorous physical activity, both in 1-2 tests (OR:1.73, 95% confidence interval (CI): 1.32-2.26) and in 3+tests (OR: 3.36, 95% CI: 2.57-4.40).
CONCLUSIONS: Cognitive impairment presented low prevalence and was associated with low levels of handgrip strength and physical inactivity. These specific factors may play a special role in early detection, diagnosis, and treatment or may slow down the progression of cognitive impairment.
METHODS: Data were collected from 41,395 adults from 27 European countries participating in the Survey of Health, Ageing, and Retirement in Europe (SHARE) during 2019-2020. Cognitive function was assessed based on five tests, and cognitive impairment was defined using 3+tests. Handgrip strength and physical inactivity were also correlated through the analysis of covariance using a complex study design.
RESULTS: The majority of participants were female (56.6%), with a mean age of 70.9 years, and 22.6% presented multimorbidity. Furthermore, 51.1% had a normal cognitive function, while 13.3% had cognitive impairment (The estimated population was 21,944,722). Moreover, cognitive impairment was more prevalent in females than in males (14.4% vs. 12.0%, P<0.001) in patients with no years of education (P<0.001) and origin from southern European countries (P<0.001). Additionally, participants with cognitive impairment had lower mean handgrip strength compared to those with cognitive impairment in 1-2 criteria or with normal cognitive function (29.3 vs. 33.4 and 35.1 kg, respectively, P<0.001). Physically inactive participants had higher odds ratio (OR) of cognitive impairment than those engaging in moderate/vigorous physical activity, both in 1-2 tests (OR:1.73, 95% confidence interval (CI): 1.32-2.26) and in 3+tests (OR: 3.36, 95% CI: 2.57-4.40).
CONCLUSIONS: Cognitive impairment presented low prevalence and was associated with low levels of handgrip strength and physical inactivity. These specific factors may play a special role in early detection, diagnosis, and treatment or may slow down the progression of cognitive impairment.
摘要：
背景：认知功能在衰老过程中至关重要。这项研究评估了欧洲50岁及以上成年人的认知功能与握力和身体不活动的关系。研究设计：这是一项横断面调查。
方法：数据来自27个欧洲国家参与健康调查的41,395名成年人。老龄化,2019-2020年期间在欧洲退休（分享）。根据五项测试评估认知功能，使用3+测试定义认知障碍。通过使用复杂的研究设计进行协方差分析，手柄力量和身体不活动也相关。
结果：大多数参与者是女性（56.6％），平均年龄为70.9岁，22.6%的患者呈现多浊度。此外，51.1%的人认知功能正常,而13.3%的人有认知障碍(估计人口为21,944,722)。此外，认知障碍在女性比男性更普遍(14.4%vs.12.0%,P<0.001）在没有受教育年限（P<0.001）且来自南欧国家（P<0.001）的患者中。此外,与1-2个标准的认知障碍患者或认知功能正常患者相比，认知障碍患者的平均握力较低(29.3vs.33.4和35.1公斤，分别,P<0.001)。不从事身体活动的参与者比从事中等/剧烈身体活动的参与者有更高的认知障碍比值比（OR）。1-2检验（OR：1.73，95％置信区间（CI）：1.32-2.26）和3检验（OR：3.36，95％CI：2.57-4.40）。
结论：认知障碍的患病率较低，并且与低水平的握力和缺乏体力活动有关。这些特定因素可能在早期发现中起特殊作用，诊断,和治疗或可能减缓认知障碍的进展。
方法：数据来自27个欧洲国家参与健康调查的41,395名成年人。老龄化,2019-2020年期间在欧洲退休（分享）。根据五项测试评估认知功能，使用3+测试定义认知障碍。通过使用复杂的研究设计进行协方差分析，手柄力量和身体不活动也相关。
结果：大多数参与者是女性（56.6％），平均年龄为70.9岁，22.6%的患者呈现多浊度。此外，51.1%的人认知功能正常,而13.3%的人有认知障碍(估计人口为21,944,722)。此外，认知障碍在女性比男性更普遍(14.4%vs.12.0%,P<0.001）在没有受教育年限（P<0.001）且来自南欧国家（P<0.001）的患者中。此外,与1-2个标准的认知障碍患者或认知功能正常患者相比，认知障碍患者的平均握力较低(29.3vs.33.4和35.1公斤，分别,P<0.001)。不从事身体活动的参与者比从事中等/剧烈身体活动的参与者有更高的认知障碍比值比（OR）。1-2检验（OR：1.73，95％置信区间（CI）：1.32-2.26）和3检验（OR：3.36，95％CI：2.57-4.40）。
结论：认知障碍的患病率较低，并且与低水平的握力和缺乏体力活动有关。这些特定因素可能在早期发现中起特殊作用，诊断,和治疗或可能减缓认知障碍的进展。
