PDF(Pubmed)
Abstract：
This study investigated the morphology of the functional near-infrared spectroscopy (fNIRS) response to speech sounds measured from 16 sleeping infants and how it changes with repeated stimulus presentation. We observed a positive peak followed by a wide negative trough, with the latter being most evident in early epochs. We argue that the overall response morphology captures the effects of two simultaneous, but independent, response mechanisms that are both activated at the stimulus onset: one being the obligatory response to a sound stimulus by the auditory system, and the other being a neural suppression effect induced by the arousal system. Because the two effects behave differently with repeated epochs, it is possible to mathematically separate them and use fNIRS to study factors that affect the development and activation of the arousal system in infants. The results also imply that standard fNIRS analysis techniques need to be adjusted to take into account the possibilities of multiple simultaneous brain systems being activated and that the response to a stimulus is not necessarily stationary.
摘要：
这项研究调查了功能性近红外光谱（fNIRS）对16名睡眠婴儿测得的语音声音的反应形态，以及它如何随着重复的刺激表现而变化。我们观察到一个正峰，然后是一个宽的负谷，后者在早期最明显。我们认为，整体反应形态捕获了两个同时，但独立，在刺激开始时都被激活的反应机制：一种是听觉系统对声音刺激的强制性反应，另一种是唤醒系统引起的神经抑制作用。因为这两种效应在重复的时期表现不同，可以在数学上将它们分开，并使用fNIRS研究影响婴儿唤醒系统发育和激活的因素。结果还暗示，需要调整标准fNIRS分析技术，以考虑多个同时激活大脑系统的可能性，并且对刺激的反应不一定是静止的。
