METHODS: Original peer-reviewed articles conducting ACC measurements in children (< 18 years). Data were extracted and summarised for: (1) participant characteristics; (2) ACC methods and auditory stimuli; (3) information related to the performance of the ACC technique; (4) ACC measurement outcomes, advantages, and challenges. The systematic review was conducted using PRISMA guidelines for reporting and the methodological quality of included articles was assessed.
RESULTS: A total of 28 studies were identified (9 infant studies). Review results show that ACC responses can be measured in infants (from < 3 months), and there is evidence of age-dependency, including increased robustness of the ACC response with increasing childhood age. Clinical applications include the measurement of the neural capacity for speech and non-speech sound discrimination in children with hearing loss, auditory neuropathy spectrum disorder (ANSD) and central auditory processing disorder (CAPD). Additionally, ACCs can be recorded in children with hearing aids, auditory brainstem implants, and cochlear implants, and ACC results may guide hearing intervention/rehabilitation strategies. The review identified that the time taken to perform ACC measurements was often lengthy; the development of more efficient ACC test procedures for children would be beneficial. Comparisons between objective ACC measurements and behavioural measures of sound discrimination showed significant correlations for some, but not all, included studies.
CONCLUSIONS: ACC measurements of the neural capacity to discriminate between speech and non-speech sounds are feasible in infants and children, and a wide range of possible clinical applications exist, although more time-efficient procedures would be advantageous for clinical uptake. A consideration of age and maturational effects is recommended, and further research is required to investigate the relationship between objective ACC measures and behavioural measures of sound and speech perception for effective clinical implementation.
方法:在儿童(<18岁)中进行ACC测量的原始同行评审文章。数据被提取和总结为:(1)参与者特征;(2)ACC方法和听觉刺激;(3)与ACC技术性能相关的信息;(4)ACC测量结果,优势,和挑战。使用PRISMA报告指南进行系统审查,并评估纳入文章的方法学质量。
结果:共确定了28项研究(9项婴儿研究)。审查结果表明,ACC反应可以测量婴儿(从<3个月),有证据表明年龄依赖性,包括随着儿童年龄的增加,ACC反应的稳健性增加。临床应用包括测量听力损失儿童的言语和非言语声音辨别的神经能力,听觉神经病变谱系障碍(ANSD)和中枢听觉处理障碍(CAPD)。此外,ACCs可以记录在有助听器的儿童身上,听觉脑干植入物,和人工耳蜗,和ACC结果可以指导听力干预/康复策略。审查发现,进行ACC测量所需的时间通常很长;为儿童开发更有效的ACC测试程序将是有益的。客观的ACC测量值与声音辨别的行为测量值之间的比较显示出某些显着的相关性,但不是全部,包括研究。
结论:ACC测量区分语音和非语音的神经能力在婴儿和儿童中是可行的,并且存在广泛的可能的临床应用,虽然时间更有效的程序将有利于临床摄取。建议考虑年龄和成熟效应,需要进一步研究以调查客观ACC措施与声音和言语感知的行为措施之间的关系,以便有效地进行临床实施。