PDF(Pubmed)
Abstract：
OBJECTIVE: This study was designed to investigate retinal nerve fiber layer circumpapillary optical coherence tomography to determine posterior vitreous detachment (PVD) status and to develop a clinically relevant PVD grading scale based on retinal nerve fiber layer circumpapillary optical coherence tomography to determine the incidence of PVD by age and association with vitreomacular traction disorders.
METHODS: Ophthalmic images and medical records of patients with retinal diseases were retrospectively analyzed by three masked graders using retinal nerve fiber layer circumpapillary optical coherence tomography and macular optical coherence tomography. Based on PVD status, eyes were categorized into five newly defined PVD stages.
RESULTS: Among 2002 eyes, PVD stages were as follows: A) 25 (1.25%); B) 725 (36.21%); C-) 248 (12.39%); C+) 151 (7.54%); D) 851 (42.51%); X) 2 (0.1%). Posterior vitreous detachment was correlated with advanced age (P < 0.0001). Limited separation or partial separation between lamella within the posterior vitreous cortex (Stage B) was noted early (68% of eyes <18 years). Overall, 34% of eyes >70 years did not exhibit complete PVD. Of 75 eyes with tractional vitreoretinal disorders, 64 (85.3%) were Stage C-/C+, identifying Stage C as the high-risk \"complication\" stage.
CONCLUSIONS: Imaging analyses using retinal nerve fiber layer circumpapillary optical coherence tomography and macular optical coherence tomography scans in conjunction allow rapid assessment of the PVD stage. These techniques can assist clinicians and surgeons in counseling patients and planning surgical approaches. Observations confirmed the progression of PVD through predictable stages and the progression of PVD with age.
METHODS: Ophthalmic images and medical records of patients with retinal diseases were retrospectively analyzed by three masked graders using retinal nerve fiber layer circumpapillary optical coherence tomography and macular optical coherence tomography. Based on PVD status, eyes were categorized into five newly defined PVD stages.
RESULTS: Among 2002 eyes, PVD stages were as follows: A) 25 (1.25%); B) 725 (36.21%); C-) 248 (12.39%); C+) 151 (7.54%); D) 851 (42.51%); X) 2 (0.1%). Posterior vitreous detachment was correlated with advanced age (P < 0.0001). Limited separation or partial separation between lamella within the posterior vitreous cortex (Stage B) was noted early (68% of eyes <18 years). Overall, 34% of eyes >70 years did not exhibit complete PVD. Of 75 eyes with tractional vitreoretinal disorders, 64 (85.3%) were Stage C-/C+, identifying Stage C as the high-risk \"complication\" stage.
CONCLUSIONS: Imaging analyses using retinal nerve fiber layer circumpapillary optical coherence tomography and macular optical coherence tomography scans in conjunction allow rapid assessment of the PVD stage. These techniques can assist clinicians and surgeons in counseling patients and planning surgical approaches. Observations confirmed the progression of PVD through predictable stages and the progression of PVD with age.
摘要：
目的：本研究旨在研究视网膜神经纤维层周边光学相干断层扫描，以确定玻璃体后脱离（PVD）状态，并基于视网膜神经纤维层周边光学相干断层扫描制定临床相关的PVD分级量表，以确定年龄和与玻璃体黄斑牵引障碍的关系。
方法：采用视网膜神经纤维层周边乳头光学相干断层扫描和黄斑光学相干断层扫描对视网膜疾病患者的眼科图像和病历进行回顾性分析。根据PVD状态，眼睛被分为五个新定义的PVD阶段.
结果：在2002年的眼睛中，PVD阶段如下:A)25(1.25%);B)725(36.21%);C-)248(12.39%);C+)151(7.54%);D)851(42.51%);X)2(0.1%)。玻璃体后脱离与高龄相关(P<0.0001)。早期注意到玻璃体后皮质内薄层之间的有限分离或部分分离（B期）（68％的眼睛<18岁）。总的来说,34%>70岁的眼睛没有表现出完全的PVD。在75只患有牵引性玻璃体视网膜疾病的眼睛中，64（85.3%）为C-/C+阶段，确定C阶段为高危“并发症”阶段。
结论：结合使用视网膜神经纤维层周边乳头光学相干断层扫描和黄斑光学相干断层扫描的成像分析可以快速评估PVD阶段。这些技术可以帮助临床医生和外科医生为患者提供咨询和计划手术方法。观察结果证实了PVD通过可预测阶段的进展以及PVD随年龄的进展。
方法：采用视网膜神经纤维层周边乳头光学相干断层扫描和黄斑光学相干断层扫描对视网膜疾病患者的眼科图像和病历进行回顾性分析。根据PVD状态，眼睛被分为五个新定义的PVD阶段.
结果：在2002年的眼睛中，PVD阶段如下:A)25(1.25%);B)725(36.21%);C-)248(12.39%);C+)151(7.54%);D)851(42.51%);X)2(0.1%)。玻璃体后脱离与高龄相关(P<0.0001)。早期注意到玻璃体后皮质内薄层之间的有限分离或部分分离（B期）（68％的眼睛<18岁）。总的来说,34%>70岁的眼睛没有表现出完全的PVD。在75只患有牵引性玻璃体视网膜疾病的眼睛中，64（85.3%）为C-/C+阶段，确定C阶段为高危“并发症”阶段。
结论：结合使用视网膜神经纤维层周边乳头光学相干断层扫描和黄斑光学相干断层扫描的成像分析可以快速评估PVD阶段。这些技术可以帮助临床医生和外科医生为患者提供咨询和计划手术方法。观察结果证实了PVD通过可预测阶段的进展以及PVD随年龄的进展。
