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Abstract：
OBJECTIVE: The objective of this study was to assess the clinical and uterine cervix characteristics of patients displaying vaginal discharge with positive results for Mycoplasma sp. and/or Ureaplasma spp.
METHODS: An analytical cross-sectional study involving women aged 18-45 years was conducted. Microbiological assessments included Ureaplasma and Mycoplasma cultures, as well as human papillomavirus hybrid capture using ecto and endocervix swabs. All tests were two-tailed, and significance was set at p<0.05.
RESULTS: Among 324 women, Ureaplasma prevalence was 17.9%, and Mycoplasma prevalence was 3.1%. The Ureaplasma-positive group exhibited a higher frequency of urinary tract infections (39.1 vs. 19%, p=0.002) and human papillomavirus (39.7 vs. 12.8%, p≤0.001) compared with controls. The Mycoplasma-positive group showed a higher frequency of non-contraceptive use compared with controls (66.2 vs. 30.0%, p=0.036). Abnormal colposcopic findings were more prevalent in the Mycoplasma/Ureaplasma-positive group than in controls (positive: 65% vs. control: 35%, p=0.001). Pap smear findings did not differ between the groups.
CONCLUSIONS: Ureaplasma spp. was associated with urinary tract infections and human papillomavirus, while the presence of Mycoplasma sp. was linked to reduced contraceptive use. When analyzing both pathogens together, a higher frequency of abnormal colposcopic findings was observed, with no difference in cytological findings in the positive group.
METHODS: An analytical cross-sectional study involving women aged 18-45 years was conducted. Microbiological assessments included Ureaplasma and Mycoplasma cultures, as well as human papillomavirus hybrid capture using ecto and endocervix swabs. All tests were two-tailed, and significance was set at p<0.05.
RESULTS: Among 324 women, Ureaplasma prevalence was 17.9%, and Mycoplasma prevalence was 3.1%. The Ureaplasma-positive group exhibited a higher frequency of urinary tract infections (39.1 vs. 19%, p=0.002) and human papillomavirus (39.7 vs. 12.8%, p≤0.001) compared with controls. The Mycoplasma-positive group showed a higher frequency of non-contraceptive use compared with controls (66.2 vs. 30.0%, p=0.036). Abnormal colposcopic findings were more prevalent in the Mycoplasma/Ureaplasma-positive group than in controls (positive: 65% vs. control: 35%, p=0.001). Pap smear findings did not differ between the groups.
CONCLUSIONS: Ureaplasma spp. was associated with urinary tract infections and human papillomavirus, while the presence of Mycoplasma sp. was linked to reduced contraceptive use. When analyzing both pathogens together, a higher frequency of abnormal colposcopic findings was observed, with no difference in cytological findings in the positive group.
摘要：
目的：本研究的目的是评估支原体阳性结果为阴道分泌物的患者的临床和子宫颈特征。和/或脲原体属。
方法：进行了一项涉及18-45岁女性的横断面分析研究。微生物学评估包括脲原体和支原体培养物，以及使用ecto和宫颈内膜拭子捕获人乳头瘤病毒杂种。所有测试都是双尾的，并且显著性设定为p<0.05。
结果：在324名女性中，脲原体患病率为17.9%,支原体患病率为3.1%。脲原体阳性组尿路感染的频率更高（39.1vs.19%,p=0.002）和人乳头瘤病毒（39.7vs.12.8%,p≤0.001)与对照组相比。与对照组相比，支原体阳性组的非避孕药具使用频率更高（66.2vs.30.0%,p=0.036)。支原体/脲原体阳性组的阴道镜异常发现比对照组更为普遍（阳性：65％vs.控制：35%，p=0.001)。两组之间的巴氏涂片检查结果没有差异。
结论：脲原体属。与尿路感染和人乳头瘤病毒有关，而支原体的存在。与减少避孕药具的使用有关。当一起分析两种病原体时，观察到阴道镜异常发现的频率更高，阳性组的细胞学结果无差异。
方法：进行了一项涉及18-45岁女性的横断面分析研究。微生物学评估包括脲原体和支原体培养物，以及使用ecto和宫颈内膜拭子捕获人乳头瘤病毒杂种。所有测试都是双尾的，并且显著性设定为p<0.05。
结果：在324名女性中，脲原体患病率为17.9%,支原体患病率为3.1%。脲原体阳性组尿路感染的频率更高（39.1vs.19%,p=0.002）和人乳头瘤病毒（39.7vs.12.8%,p≤0.001)与对照组相比。与对照组相比，支原体阳性组的非避孕药具使用频率更高（66.2vs.30.0%,p=0.036)。支原体/脲原体阳性组的阴道镜异常发现比对照组更为普遍（阳性：65％vs.控制：35%，p=0.001)。两组之间的巴氏涂片检查结果没有差异。
结论：脲原体属。与尿路感染和人乳头瘤病毒有关，而支原体的存在。与减少避孕药具的使用有关。当一起分析两种病原体时，观察到阴道镜异常发现的频率更高，阳性组的细胞学结果无差异。
