Abstract：
The pancreas is adjacent to critical organs; excessive microwave ablation (MWA) can result in serious complications. The purpose of this paper is to provide the reference data of pancreas MWA for clinicians, analyze the ablation outcomes under different ablation parameters, and determine the critical temperature of pancreatic surface fat liquefaction outflow. Combinations of two power levels (30 W and 55 W), three antenna diameters (1.3 mm, 1.6 mm, and 1.9 mm), and three ablation times (1 min, 1.5 min, and 2 min) were applied to an ex vivo pig pancreas. Temperature measurements were taken at four thermocouple points. The center point is located 5 mm horizontally from the antenna slot, with a temperature measurement point located 5 mm above, below, and to the right of the center point. Main effect analysis and variance analysis were used to quantify the influences of each factor on the ablation outcomes. At 30 W, the antenna diameter contributing the most at 48.5%. At 30 W-1.3 mm-1 min, the spherical index (1.41) is closest to 1. At 55 W, the coagulation zone size was almost only affected by the ablation time, with a contribution rate of 28.7%, the temperature at point C exceeds point B. On the surface of the ex vivo porcine pancreas, the fat outflow temperature was 54ã. Ablation combinations with low power, short duration, and small antenna diameter results in a more nearly spherical coagulation zone. When performing MWA on the pancreas, it is advisable to avoid areas with higher fat content, while keeping the pancreatic surface temperature below 54°C.
摘要：
胰腺与关键器官相邻；过度微波消融（MWA）会导致严重的并发症。本文旨在为临床医生提供胰腺MWA的参考数据,分析不同消融参数下的消融结果，并确定胰腺表面脂肪液化流出的临界温度。两种功率电平的组合（30W和55W），三个天线直径(1.3毫米，1.6mm,和1.9毫米），和三次消融时间(1分钟，1.5min,和2分钟）应用于离体猪胰腺。在四个热电偶点处进行温度测量。中心点位于距天线槽5mm的水平位置,温度测量点位于5毫米以上，下面,在中心点的右边。采用主效应分析和方差分析量化各因素对消融结果的影响。在30瓦，天线直径贡献最大，为48.5%。在30W-1.3mm-1分钟时，球面指数(1.41)最接近1。在55W时，凝血区大小几乎仅受消融时间的影响，贡献率为28.7%，C点的温度超过B点。在离体猪胰腺的表面，脂肪流出温度为54℃。低功率消融组合,持续时间短,和小的天线直径导致更接近球形的凝结区。对胰腺进行MWA时，建议避免脂肪含量较高的区域，同时保持胰腺表面温度低于54°C。
