PDF(Pubmed)
Abstract：
The auditory system can selectively attend to the target source in complex environments, the phenomenon known as the \"cocktail party\" effect. However, the spatiotemporal dynamics of electrophysiological activity associated with auditory selective spatial attention (ASSA) remain largely unexplored. In this study, single-source and multiple-source paradigms were designed to simulate different auditory environments, and microstate analysis was introduced to reveal the electrophysiological correlates of ASSA. Furthermore, cortical source analysis was employed to reveal the neural activity regions of these microstates. The results showed that five microstates could explain the spatiotemporal dynamics of ASSA, ranging from MS1 to MS5. Notably, MS2 and MS3 showed significantly lower partial properties in multiple-source situations than in single-source situations, whereas MS4 had shorter durations and MS5 longer durations in multiple-source situations than in single-source situations. MS1 had insignificant differences between the two situations. Cortical source analysis showed that the activation regions of these microstates initially transferred from the right temporal cortex to the temporal-parietal cortex, and subsequently to the dorsofrontal cortex. Moreover, the neural activity of the single-source situations was greater than that of the multiple-source situations in MS2 and MS3, correlating with the N1 and P2 components, with the greatest differences observed in the superior temporal gyrus and inferior parietal lobule. These findings suggest that these specific microstates and their associated activation regions may serve as promising substrates for decoding ASSA in complex environments.
摘要：
在复杂的环境中，听觉系统可以有选择地关注目标源，这种现象被称为“鸡尾酒派对”效应。然而,与听觉选择性空间注意(ASSA)相关的电生理活动的时空动力学在很大程度上仍未被探索.在这项研究中,设计了单源和多源范例来模拟不同的听觉环境，引入微态分析以揭示ASSA的电生理相关性。此外，皮层源分析用于揭示这些微状态的神经活动区域。结果表明，五种微观状态可以解释ASSA的时空动力学，范围从MS1到MS5。值得注意的是,MS2和MS3在多源情况下的部分属性明显低于单源情况。与单源情况相比,多源情况下MS4的持续时间较短,MS5的持续时间较长.两种情况之间的MS1差异不显著。皮质来源分析表明，这些微状态的激活区域最初从右颞叶皮层转移到颞叶顶叶皮层，随后进入背额叶皮层。此外，在MS2和MS3中，单源情况的神经活动大于多源情况的神经活动，与N1和P2分量相关，在颞上回和下顶叶小叶中观察到最大的差异。这些发现表明，这些特定的微状态及其相关的激活区域可以作为在复杂环境中解码ASSA的有希望的底物。
