Abstract：
UNASSIGNED: To explore the complications and pregnancy outcomes of vaginal dinoprostone vs. Cook\'s double balloon for the induction of labor among pregnancies complicated by small-for-gestational-age (SGA) at term.
UNASSIGNED: This retrospective study included consecutive singleton pregnancies complicated by SGA treated at Fujian Maternity and Child Health Hospital between January 2017 and December 2021. The patients were divided into the Cook\'s double balloon and dinoprostone groups according to the induction method they received. The primary outcome was vaginal delivery.
UNASSIGNED: This study included 318 women [165 (aged 30.25 ± 4.72 years) and 153 (aged 28.80 ± 3.91 years) in the dinoprostone and Cook\'s balloon groups]. The dinoprostone group had a higher vaginal delivery rate than the Cook\'s balloon group (83.6% vs. 71.9%, p = .012). The cervical ripening duration (9.73 ± 4.82 vs. 17.50 ± 8.77 h, p < .001) and induction to delivery duration (22.11 ± 8.13 vs. 30.27 ± 12.28, p < .001) were significantly shorter in the dinoprostone group compared with the Cook\'s balloon group. Less women needed oxytocin infusion in the dinoprostone group compared with that in the Cook\'s balloon group (32.7% vs. 86.3%, p < .001). Dinoprostone was independently associated with vaginal delivery (HR = 1.756, 95%CI: 1.286-2.399, p = .000). The rates of uterine tachysystole and spontaneous rupture of the fetal membrane were significantly higher in the dinoprostone group than that in the Cook\'s balloon group (10.3% vs. 0.7%, p < .001; 7.3% vs. 1.3%, p = .012). There were no differences in maternal complications and neonatal outcomes between the two groups.
UNASSIGNED: In pregnant woman with pregnancies complicated by SGA, cervical ripening using dinoprostone were more likely to achieve vaginal delivery than those with Cook\'s balloon, and with a favorable complication profile.
UNASSIGNED: This retrospective study included consecutive singleton pregnancies complicated by SGA treated at Fujian Maternity and Child Health Hospital between January 2017 and December 2021. The patients were divided into the Cook\'s double balloon and dinoprostone groups according to the induction method they received. The primary outcome was vaginal delivery.
UNASSIGNED: This study included 318 women [165 (aged 30.25 ± 4.72 years) and 153 (aged 28.80 ± 3.91 years) in the dinoprostone and Cook\'s balloon groups]. The dinoprostone group had a higher vaginal delivery rate than the Cook\'s balloon group (83.6% vs. 71.9%, p = .012). The cervical ripening duration (9.73 ± 4.82 vs. 17.50 ± 8.77 h, p < .001) and induction to delivery duration (22.11 ± 8.13 vs. 30.27 ± 12.28, p < .001) were significantly shorter in the dinoprostone group compared with the Cook\'s balloon group. Less women needed oxytocin infusion in the dinoprostone group compared with that in the Cook\'s balloon group (32.7% vs. 86.3%, p < .001). Dinoprostone was independently associated with vaginal delivery (HR = 1.756, 95%CI: 1.286-2.399, p = .000). The rates of uterine tachysystole and spontaneous rupture of the fetal membrane were significantly higher in the dinoprostone group than that in the Cook\'s balloon group (10.3% vs. 0.7%, p < .001; 7.3% vs. 1.3%, p = .012). There were no differences in maternal complications and neonatal outcomes between the two groups.
UNASSIGNED: In pregnant woman with pregnancies complicated by SGA, cervical ripening using dinoprostone were more likely to achieve vaginal delivery than those with Cook\'s balloon, and with a favorable complication profile.
摘要：
■探讨阴道地诺前列酮的并发症和妊娠结局Cook的双球囊用于足月妊娠合并小于胎龄（SGA）的引产。
这项回顾性研究包括2017年1月至2021年12月在福建省妇幼保健院接受SGA治疗的连续单胎妊娠。根据所接受的诱导方法将患者分为Cook's双球囊组和地诺前列酮组。主要结果是阴道分娩。
■这项研究包括318名妇女[165名（年龄30.25±4.72岁）和153名（年龄28.80±3.91岁）在地诺前列酮和库克的气球组]。地诺前列酮组的阴道分娩率高于库克气球组（83.6%vs.71.9%,p=.012）。宫颈成熟持续时间(9.73±4.82vs.17.50±8.77h,p<.001)和诱导至分娩持续时间(22.11±8.13vs.与Cook\'s气球组相比，地诺前列酮组的30.27±12.28，p<.001）显着缩短。与库克气球组相比，地诺前列酮组需要输注催产素的女性较少(32.7%vs.86.3%,p<.001)。地诺前列酮与阴道分娩独立相关(HR=1.756,95CI:1.286-2.399,p=.000)。地诺前列酮组的子宫收缩和胎膜自发性破裂的发生率明显高于Cook\'s球囊组（10.3％vs.0.7%，p<.001；7.3%与1.3%,p=.012）。两组产妇并发症及新生儿结局差异无统计学意义。
■在妊娠合并SGA的孕妇中，使用地诺前列酮的宫颈成熟比使用Cook\'s气球的宫颈成熟更有可能实现阴道分娩，并具有良好的并发症特征。
这项回顾性研究包括2017年1月至2021年12月在福建省妇幼保健院接受SGA治疗的连续单胎妊娠。根据所接受的诱导方法将患者分为Cook's双球囊组和地诺前列酮组。主要结果是阴道分娩。
■这项研究包括318名妇女[165名（年龄30.25±4.72岁）和153名（年龄28.80±3.91岁）在地诺前列酮和库克的气球组]。地诺前列酮组的阴道分娩率高于库克气球组（83.6%vs.71.9%,p=.012）。宫颈成熟持续时间(9.73±4.82vs.17.50±8.77h,p<.001)和诱导至分娩持续时间(22.11±8.13vs.与Cook\'s气球组相比，地诺前列酮组的30.27±12.28，p<.001）显着缩短。与库克气球组相比，地诺前列酮组需要输注催产素的女性较少(32.7%vs.86.3%,p<.001)。地诺前列酮与阴道分娩独立相关(HR=1.756,95CI:1.286-2.399,p=.000)。地诺前列酮组的子宫收缩和胎膜自发性破裂的发生率明显高于Cook\'s球囊组（10.3％vs.0.7%，p<.001；7.3%与1.3%,p=.012）。两组产妇并发症及新生儿结局差异无统计学意义。
■在妊娠合并SGA的孕妇中，使用地诺前列酮的宫颈成熟比使用Cook\'s气球的宫颈成熟更有可能实现阴道分娩，并具有良好的并发症特征。
