Abstract：
BACKGROUND: To assess changes in ocular biometry of the phakic eye after pars-plana-vitrectomy (PPV) and silicone oil (SO) endotamponade in eyes with a retinal detachment.
METHODS: This retrospective, consecutive case series included 72 eyes of 72 patients who underwent PPV with 5000-centistokes SO endotamponade between July 2018 and June 2023. Pseudophakic eyes and eyes with a combined phacovitrectomy were excluded. Primary endpoints were keratometry values, anterior chamber depth (ACD), lens thickness (LT), horizontal corneal diameter (HCD), and axial length (AL) measured by swept-source optical coherence tomography-based biometry (IOLMaster 700) preoperatively and six weeks postoperatively. A recently described formula was used to adjust the AL (aAL) in eyes with SO endotamponade and a theoretical intraocular lens (IOL) calculation was performed.
RESULTS: The mean age was 62.1 ± 8.3 years (range: 37-85). After PPV with SO fill, there was an increase in Kmean (0.19 ± 0.51D), while ACD (0.05 ± 0.13 mm), LT (0.03 ± 0.14 mm), and HCD (0.02 ± 0.24 mm) decreased. Preoperatively, the mean AL was 25.22 ± 1.78 mm, while postoperatively the AL was overestimated by 0.12 ± 0.42 mm on average (p = 0.04). By adjusting the AL, the mean difference could be reduced to -0.002 ± 0.41 mm. The aAL resulted in a difference in the refractive outcome in eyes with an AL > 25 mm of 0.34 ± 0.10D in the IOL calculation.
CONCLUSIONS: While changes in biometry after PPV with SO endotamponade in the anterior segment are clinically less relevant, a considerable overestimation of AL with IOLMaster 700 was found. We recommend the use of a recently introduced formula for adjusting AL in eyes with SO, allowing overestimation to be minimised considerably.
METHODS: This retrospective, consecutive case series included 72 eyes of 72 patients who underwent PPV with 5000-centistokes SO endotamponade between July 2018 and June 2023. Pseudophakic eyes and eyes with a combined phacovitrectomy were excluded. Primary endpoints were keratometry values, anterior chamber depth (ACD), lens thickness (LT), horizontal corneal diameter (HCD), and axial length (AL) measured by swept-source optical coherence tomography-based biometry (IOLMaster 700) preoperatively and six weeks postoperatively. A recently described formula was used to adjust the AL (aAL) in eyes with SO endotamponade and a theoretical intraocular lens (IOL) calculation was performed.
RESULTS: The mean age was 62.1 ± 8.3 years (range: 37-85). After PPV with SO fill, there was an increase in Kmean (0.19 ± 0.51D), while ACD (0.05 ± 0.13 mm), LT (0.03 ± 0.14 mm), and HCD (0.02 ± 0.24 mm) decreased. Preoperatively, the mean AL was 25.22 ± 1.78 mm, while postoperatively the AL was overestimated by 0.12 ± 0.42 mm on average (p = 0.04). By adjusting the AL, the mean difference could be reduced to -0.002 ± 0.41 mm. The aAL resulted in a difference in the refractive outcome in eyes with an AL > 25 mm of 0.34 ± 0.10D in the IOL calculation.
CONCLUSIONS: While changes in biometry after PPV with SO endotamponade in the anterior segment are clinically less relevant, a considerable overestimation of AL with IOLMaster 700 was found. We recommend the use of a recently introduced formula for adjusting AL in eyes with SO, allowing overestimation to be minimised considerably.
摘要：
背景：评估视网膜脱离眼的平坦部玻璃体切除术（PPV）和硅油（SO）内填塞后有晶状体眼的眼部生物测量变化。
方法：本回顾性研究，连续病例系列包括在2018年7月至2023年6月期间接受PPV治疗的72例患者的72只眼睛,这些患者在5,000厘斯内填塞.排除了假晶状体眼和联合晶状体切除术的眼睛。主要终点是角膜曲率测量值，前房深度（ACD），透镜厚度(LT),角膜水平直径(HCD),术前和术后六周通过基于扫频源光学相干断层扫描的生物测量（IOLMaster700）测量的轴向长度（AL）。使用最近描述的公式来调整具有SO内填充剂的眼睛中的AL（aAL），并进行了理论人工晶状体（IOL）计算。
结果：平均年龄为62.1±8.3岁（范围：37-85岁）。在使用SO填充的PPV之后，Kmean增加（0.19±0.51D），而ACD(0.05±0.13mm),LT(0.03±0.14mm),HCD(0.02±0.24mm)下降。术前,平均AL为25.22±1.78mm，而术后AL平均高估了0.12±0.42mm（p=0.04）。通过调整AL，平均差可降至-0.002±0.41mm。aAL导致在IOL计算中AL>25mm为0.34±0.10D的眼睛中屈光结果的差异。
结论：虽然在前段有SO内填充的PPV后，生物测量的变化在临床上较不相关，发现IOLMaster700对AL的高估。我们建议使用最近引入的公式来调整带有SO的眼睛中的AL，允许高估被大大减少。
方法：本回顾性研究，连续病例系列包括在2018年7月至2023年6月期间接受PPV治疗的72例患者的72只眼睛,这些患者在5,000厘斯内填塞.排除了假晶状体眼和联合晶状体切除术的眼睛。主要终点是角膜曲率测量值，前房深度（ACD），透镜厚度(LT),角膜水平直径(HCD),术前和术后六周通过基于扫频源光学相干断层扫描的生物测量（IOLMaster700）测量的轴向长度（AL）。使用最近描述的公式来调整具有SO内填充剂的眼睛中的AL（aAL），并进行了理论人工晶状体（IOL）计算。
结果：平均年龄为62.1±8.3岁（范围：37-85岁）。在使用SO填充的PPV之后，Kmean增加（0.19±0.51D），而ACD(0.05±0.13mm),LT(0.03±0.14mm),HCD(0.02±0.24mm)下降。术前,平均AL为25.22±1.78mm，而术后AL平均高估了0.12±0.42mm（p=0.04）。通过调整AL，平均差可降至-0.002±0.41mm。aAL导致在IOL计算中AL>25mm为0.34±0.10D的眼睛中屈光结果的差异。
结论：虽然在前段有SO内填充的PPV后，生物测量的变化在临床上较不相关，发现IOLMaster700对AL的高估。我们建议使用最近引入的公式来调整带有SO的眼睛中的AL，允许高估被大大减少。
