综合分析强调了三维基因组和 DNA 之间的相互作用 ,转移性前列腺癌的 RNA 和表观基因组改变。
Mesh : Humans Male DNA Methylation 5-Methylcytosine / analogs & derivatives metabolism Gene Expression Regulation, Neoplastic Epigenomics / methods Neoplasm Metastasis / genetics Genome, Human Prostatic Neoplasms / genetics pathology Epigenesis, Genetic Receptors, Androgen / genetics Chromatin / genetics Prostatic Neoplasms, Castration-Resistant / genetics pathology Oncogene Proteins, Fusion / genetics DNA / genetics Whole Genome Sequencing RNA / genetics Prognosis
来 源:
DOI:10.1038/s41588-024-01826-3
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