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Abstract：
BACKGROUND: This study assessed the agreement of ocular parameters of patients with myopia measured using Colombo intraocular lens (IOL) 2 and IOLMaster 700.
METHODS: Eighty patients (male, 22; average age, 29.14 ± 7.36 years) with myopia (159 eyes) were included in this study in May 2023. The participants\' axial length (AXL), central corneal thickness (CCT), lens thickness (LT), white-to-white distance (WTW), front flat (K1), steep (K2), mean (Km) corneal keratometry, astigmatism (Astig), J0 vector, and J45 vector were measured using the IOLMaster 700 and Colombo IOL 2. The measurements from both devices were compared using the generalized estimating equation, correlation analysis, and Bland-Altman plots.
RESULTS: With the Colombo IOL 2, lower values for K2 and J0 (odds ratio [OR] = 0.587, p = 0.033; OR = 0.779, p < 0.0001, respectively), and larger values for WTW, Astig, and J45 (OR = 1.277, OR = 1.482, OR = 1.1, all p < 0.0001) were obtained. All ocular measurements by both instruments showed positive correlations, with AXL demonstrating the strongest correlation (r = 0.9996, p < 0.0001). The intraclass correlation coefficients for AXL and CCT measured by both instruments was 0.999 and 0.988 (both p < 0.0001), and Bland-Altman plot showed 95% limits of agreement (LoA) of -0.078 to 0.11 mm and - 9.989 to 13.486 μm, respectively. The maximum absolute 95% LoA for LT, WTW, K1, K2, and J0 were relatively high, achieving 0.829 mm, 0.717 mm, 0.983 D, 0.948 D, and 0.632 D, respectively.
CONCLUSIONS: In young patients with myopia, CCT and AXL measurements obtained with the Colombo IOL 2 and IOLMaster 700 were comparable. However, WTW, LT, corneal refractive power, and astigmatism values could not be used interchangeably in clinical practice.
METHODS: Eighty patients (male, 22; average age, 29.14 ± 7.36 years) with myopia (159 eyes) were included in this study in May 2023. The participants\' axial length (AXL), central corneal thickness (CCT), lens thickness (LT), white-to-white distance (WTW), front flat (K1), steep (K2), mean (Km) corneal keratometry, astigmatism (Astig), J0 vector, and J45 vector were measured using the IOLMaster 700 and Colombo IOL 2. The measurements from both devices were compared using the generalized estimating equation, correlation analysis, and Bland-Altman plots.
RESULTS: With the Colombo IOL 2, lower values for K2 and J0 (odds ratio [OR] = 0.587, p = 0.033; OR = 0.779, p < 0.0001, respectively), and larger values for WTW, Astig, and J45 (OR = 1.277, OR = 1.482, OR = 1.1, all p < 0.0001) were obtained. All ocular measurements by both instruments showed positive correlations, with AXL demonstrating the strongest correlation (r = 0.9996, p < 0.0001). The intraclass correlation coefficients for AXL and CCT measured by both instruments was 0.999 and 0.988 (both p < 0.0001), and Bland-Altman plot showed 95% limits of agreement (LoA) of -0.078 to 0.11 mm and - 9.989 to 13.486 μm, respectively. The maximum absolute 95% LoA for LT, WTW, K1, K2, and J0 were relatively high, achieving 0.829 mm, 0.717 mm, 0.983 D, 0.948 D, and 0.632 D, respectively.
CONCLUSIONS: In young patients with myopia, CCT and AXL measurements obtained with the Colombo IOL 2 and IOLMaster 700 were comparable. However, WTW, LT, corneal refractive power, and astigmatism values could not be used interchangeably in clinical practice.
摘要：
背景：这项研究评估了使用科伦坡人工晶状体（IOL）2和IOLMaster700测量的近视患者的眼部参数的一致性。
方法：80例患者(男性，22岁；平均年龄，2023年5月，这项研究包括29.14±7.36岁）的近视（159眼）。参与者的轴向长度(AXL)，中央角膜厚度(CCT),透镜厚度(LT),白到白距离(WTW),前平板(K1),陡峭（K2），平均（Km）角膜角化术，散光（Astig），J0矢量,和J45载体使用IOLMaster700和ColomboIOL2进行测量。使用广义估计方程比较了两种设备的测量结果，相关分析，还有Bland-Altman的阴谋.
结果：对于科伦坡IOL2，K2和J0的值较低（比值比[OR]=0.587，p=0.033；OR=0.779，p<0.0001），和较大的WTW值，Astig,和J45(OR=1.277,OR=1.482,OR=1.1,均p<0.0001)。两种仪器的所有眼部测量均显示出正相关，与AXL的相关性最强(r=0.9996，p<0.0001)。两种仪器测量的AXL和CCT的组内相关系数分别为0.999和0.988（均p<0.0001），Bland-Altman图显示95％的一致性极限（LoA）为-0.078至0.11mm和-9.989至13.486μm，分别。LT的最大绝对95%LoA,WTW,K1、K2和J0相对较高，达到0.829毫米，0.717mm,0.983D,0.948D,和0.632D，分别。
结论：在年轻的近视患者中，使用ColomboIOL2和IOLMaster700获得的CCT和AXL测量值具有可比性。然而,WTW,LT,角膜屈光力,和散光值在临床实践中不能互换使用.
方法：80例患者(男性，22岁；平均年龄，2023年5月，这项研究包括29.14±7.36岁）的近视（159眼）。参与者的轴向长度(AXL)，中央角膜厚度(CCT),透镜厚度(LT),白到白距离(WTW),前平板(K1),陡峭（K2），平均（Km）角膜角化术，散光（Astig），J0矢量,和J45载体使用IOLMaster700和ColomboIOL2进行测量。使用广义估计方程比较了两种设备的测量结果，相关分析，还有Bland-Altman的阴谋.
结果：对于科伦坡IOL2，K2和J0的值较低（比值比[OR]=0.587，p=0.033；OR=0.779，p<0.0001），和较大的WTW值，Astig,和J45(OR=1.277,OR=1.482,OR=1.1,均p<0.0001)。两种仪器的所有眼部测量均显示出正相关，与AXL的相关性最强(r=0.9996，p<0.0001)。两种仪器测量的AXL和CCT的组内相关系数分别为0.999和0.988（均p<0.0001），Bland-Altman图显示95％的一致性极限（LoA）为-0.078至0.11mm和-9.989至13.486μm，分别。LT的最大绝对95%LoA,WTW,K1、K2和J0相对较高，达到0.829毫米，0.717mm,0.983D,0.948D,和0.632D，分别。
结论：在年轻的近视患者中，使用ColomboIOL2和IOLMaster700获得的CCT和AXL测量值具有可比性。然而,WTW,LT,角膜屈光力,和散光值在临床实践中不能互换使用.
