PDF(Pubmed)
Abstract：
Infertility among women, particularly those living with obesity, presents a multifaceted challenge with implications for reproductive health worldwide. Lifestyle interventions, mainly focusing on weight loss, have emerged as promising strategies to improve fertility outcomes in this population. This review aims to explore the effectiveness of various lifestyle interventions, encompassing dietary modifications and exercise regimens, in enhancing fertility outcomes among women with obesity and associated conditions such as polycystic ovary syndrome, congenital adrenal hyperplasia, type 2 diabetes mellitus, premenopause, hypothyroidism and eating disorders. Methodology of study search encompass a broad spectrum, ranging from interventions targeting weight management through slow or rapid weight loss to dietary approaches emphasizing whole food groups, specific nutrients, and dietary patterns like low-carbohydrate or ketogenic diets, as well as the Mediterranean diet. By synthesizing existing findings and recommendations, this review contributes to the understanding of lifestyle interventions in addressing infertility, with an emphasis on the population of women of reproductive age with excess weight and known or unknown infertility issues, while promoting their integration into clinical practice to optimize reproductive health and overall well-being.
摘要：
女性不孕症，特别是那些患有肥胖症的人，对全世界的生殖健康提出了多方面的挑战。生活方式干预，主要关注减肥，已经成为改善这一人群生育结果的有希望的策略。这篇综述旨在探讨各种生活方式干预措施的有效性。包括饮食调整和锻炼方案，在提高肥胖和相关疾病如多囊卵巢综合征的妇女的生育结果，先天性肾上腺增生,2型糖尿病,绝经前,甲状腺功能减退和饮食失调。研究搜索的方法涵盖了广泛的范围，从针对体重管理的干预措施到缓慢或快速减肥，再到强调整个食物组的饮食方法，特定的营养素，以及低碳水化合物或生酮饮食等饮食模式，以及地中海饮食。通过综合现有的调查结果和建议，这篇综述有助于理解生活方式干预在解决不孕症方面的作用，强调育龄妇女超重和已知或未知的不孕症问题，同时促进其融入临床实践，以优化生殖健康和整体福祉。
