PDF(Pubmed)
Abstract：
Although Prussian blue nanozymes (PBNZ) are widely applied in various fields, their catalytic mechanisms remain elusive. Here, we investigate the long-term catalytic performance of PBNZ as peroxidase (POD) and catalase (CAT) mimetics to elucidate their lifespan and underlying mechanisms. Unlike our previously reported Fe3O4 nanozymes, which exhibit depletable POD-like activity, the POD and CAT-like activities of PBNZ not only persist but slightly enhance over prolonged catalysis. We demonstrate that the irreversible oxidation of PBNZ significantly promotes catalysis, leading to self-increasing catalytic activities. The catalytic process of the pre-oxidized PBNZ can be initiated through either the conduction band pathway or the valence band pathway. In summary, we reveal that PBNZ follows a dual-path electron transfer mechanism during the POD and CAT-like catalysis, offering the advantage of a long service life.
摘要：
尽管普鲁士蓝纳米酶(PBNZ)在各个领域得到了广泛的应用,他们的催化机制仍然难以捉摸。这里,我们研究了PBNZ作为过氧化物酶（POD）和过氧化氢酶（CAT）模拟物的长期催化性能，以阐明其寿命和潜在机制。与我们之前报道的Fe3O4纳米酶不同，表现出可耗尽的POD样活性，随着长时间的催化，PBNZ的POD和CAT样活性不仅持续，而且略有增强。我们证明PBNZ的不可逆氧化显着促进催化，导致自我增加的催化活性。预氧化的PBNZ的催化过程可以通过导带途径或价带途径引发。总之,我们发现PBNZ在POD和CAT类催化过程中遵循双路径电子转移机制，提供使用寿命长的优点。
