Abstract：
There have been reports of potential health risks for people from hydrophobic organic pollutants, such as polycyclic aromatic hydrocarbons (PAHs), polychlorinated hydrocarbons (PCHs), and organophosphate flame retardants (OPFRs). When a contaminated site is used for residential housing or public utility and recreation areas, the soil-bound organic pollutants might pose a threat to human health. In this study, we investigated the contamination profiles and potential risks to human health of 15 PAHs, 6 PCHs, and 12 OPFRs in soils from four contaminated sites in China. We used an in vitro method to determine the oral bioaccessibility of soil pollutants. Total PAHs were found at concentrations ranging from 26.4 ng/g to 987 ng/g. PCHs (0.27‒14.3 ng/g) and OPFRs (6.30‒310 ng/g) were detected, but at low levels compared to earlier reports. The levels of PAHs, PCHs, and OPFRs released from contaminated soils into simulated gastrointestinal fluids ranged from 1.74% to 91.0%, 2.51% to 39.6%, and 1.37% to 96.9%, respectively. Based on both spiked and unspiked samples, we found that the oral bioaccessibility of pollutants was correlated with their logKow and molecular weight, and the total organic carbon content and pH of soils. PAHs in 13 out of 38 contaminated soil samples posed potential high risks to children. When considering oral bioaccessibility, nine soils still posed potential risks, while the risks in the remaining soils became negligible. The contribution of this paper is that it corrects the health risk of soil-bound organic pollutants by detecting bioaccessibility in actual soils from different contaminated sites.
摘要：
有报道称，疏水性有机污染物对人们有潜在的健康风险，如多环芳烃(PAHs)，多氯代烃(PCHs)，和有机磷酸酯阻燃剂(OPFRs)。当污染场地用于住宅或公用事业和娱乐区时，土壤中的有机污染物可能对人类健康构成威胁。在这项研究中,我们调查了15种多环芳烃的污染概况和对人类健康的潜在风险，6PCHs,中国四个污染地点土壤中的12个OPFRs。我们使用体外方法确定土壤污染物的口服生物可及性。发现总PAHs的浓度范围为26.4ng/g至987ng/g。检测到PCHs（0.27-14.3ng/g）和OPFRs（6.30-310ng/g），但与早期报告相比，水平较低。PAHs的水平,PCHs,从污染土壤释放到模拟胃肠液中的OPFRs范围从1.74%到91.0%，2.51%至39.6%,和1.37%到96.9%，分别。基于加标和未加标的样本，我们发现污染物的口腔生物可及性与它们的logKow和分子量相关，以及土壤总有机碳含量和pH值。38个污染土壤样本中的13个中的PAHs对儿童构成了潜在的高风险。当考虑口腔生物可及性时，九种土壤仍然存在潜在风险，而剩余土壤中的风险变得微不足道。本文的贡献在于，它通过检测来自不同污染地点的实际土壤中的生物可及性来纠正土壤束缚有机污染物的健康风险。
