关键词: Aquatic organisms Chirality Enantiomer Enantioselective distribution Enantioselective toxicity

Mesh : Pesticides / toxicity chemistry Water Pollutants, Chemical / toxicity chemistry Stereoisomerism Aquatic Organisms / drug effects Animals Humans

来  源:   DOI:10.1007/s10653-024-02102-3

Abstract:
Chiral pesticides account for about 40% of the total pesticides. In the process of using pesticides, it will inevitably flow into the surface water and even penetrate into the groundwater through surface runoff and other means, as a consequence, it affects the water environment. Although the enantiomers of chiral pesticides have the same physical and chemical properties, their distribution, ratio, metabolism, toxicity, etc. in the organism are often different, and sometimes even show completely opposite biological activities. In this article, the selective fate of different types of chiral pesticides such as organochlorine, organophosphorus, triazole, pyrethroid and other chiral pesticides in natural water bodies and sediments, acute toxicity to aquatic organisms, chronic toxicity and other aspects are summarized to further reflect the risks between the enantiomers of chiral pesticides to non-target organisms in the water environment. In this review, we hope to further explore its harm to human society through the study of the toxicity of chiral pesticide enantiomers, so as to provide data support and theoretical basis for the development and production of biochemical pesticides.
摘要:
手性农药约占农药总量的40%。在使用杀虫剂的过程中,它将不可避免地流入地表水,甚至通过地表径流和其他方式渗透到地下水中,因此,影响水环境。尽管手性农药的对映体具有相同的物理和化学性质,他们的分布,比率,新陈代谢,毒性,等。在生物体中往往是不同的,有时甚至表现出完全相反的生物活动。在这篇文章中,不同类型手性农药如有机氯的选择性命运,有机磷,三唑,拟除虫菊酯和天然水体和沉积物中的其他手性农药,对水生生物的急性毒性,从慢性毒性等方面进行综述,进一步反映手性农药对映体对水环境中非靶标生物的风险。在这次审查中,我们希望通过手性农药对映体的毒性研究,进一步探讨其对人类社会的危害,从而为生化农药的开发和生产提供数据支持和理论依据。
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