PDF(Pubmed)
Abstract：
Vibration and sound are the shaping matrix of the entire universe. Everything in nature is shaped by energy vibrating and communicating through its own sound trail. Every cell within our body vibrates at defined frequencies, generating its peculiar \"sound signature\". Mitochondria are dynamic, energy-transforming, biosynthetic, and signaling organelles that actively transduce biological information. Novel research has shown that the mitochondrial function of mammalian cells can be modulated by various energetic stimuli, including sound vibrations. Regarding acoustic vibrations, definite types of music have been reported to produce beneficial impacts on human health. In very recent studies, the effects of different sound stimuli and musical styles on cellular function and mitochondrial activity were evaluated and compared in human cells cultured in vitro, investigating the underlying responsible molecular mechanisms. This narrative review will take a multilevel trip from macro to intracellular microenvironment, discussing the intimate vibrational sound activities shaping living matter, delving deeper into the molecular mechanisms underlying the sound modulation of biological systems, and mainly focusing our discussion on novel evidence showing the competence of mitochondria in acting as energy portals capable of sensing and transducing the subtle informational biofields of sound vibration.
摘要：
振动和声音是整个宇宙的成形矩阵。自然界中的一切事物都是由能量振动和通过其自身的声音轨迹进行交流而形成的。我们身体内的每个细胞都以确定的频率振动，生成其特有的“声音签名”。线粒体是动态的,能量转换，生物合成，以及主动转导生物信息的信号细胞器。新的研究表明，哺乳动物细胞的线粒体功能可以通过各种能量刺激来调节，包括声音振动。关于声振动，据报道，特定类型的音乐对人类健康产生有益影响。在最近的研究中，在体外培养的人体细胞中，评估和比较了不同声音刺激和音乐风格对细胞功能和线粒体活性的影响，调查潜在的负责任的分子机制。这篇叙述性综述将从宏观到细胞内微环境进行多层次的旅行，讨论塑造生命物质的亲密振动声音活动，深入研究生物系统声音调制的分子机制，我们的讨论主要集中在新的证据上，这些证据表明线粒体作为能量门户的能力，能够感知和转换声音振动的微妙信息生物场。
