PDF(Pubmed)
Abstract：
This study investigates the effects of a ketogenic low-carbohydrate high-fat (LCHF) diet on body composition in healthy, young, normal-weight women. With the increasing interest in ketogenic diets for their various health benefits, this research aims to understand their impact on body composition, focusing on women who are often underrepresented in such studies. Conducting a randomized controlled feeding trial with a crossover design, this study compares a ketogenic LCHF diet to a Swedish National Food Agency (NFA)-recommended control diet over four weeks. Seventeen healthy, young, normal-weight women adhered strictly to the provided diets, with ketosis confirmed through blood β-hydroxybutyrate concentrations. Dual-energy X-ray absorptiometry (DXA) was utilized for precise body composition measurements. To avoid bias, all statistical analyses were performed blind. The findings reveal that the ketogenic LCHF diet led to a significant reduction in both lean mass (-1.45 kg 95% CI: [-1.90;-1.00]; p < 0.001) and fat mass (-0.66 kg 95% CI: [-1.00;-0.32]; p < 0.001) compared to the control diet, despite similar energy intake and physical activity levels. This study concludes that while the ketogenic LCHF diet is effective for weight loss, it disproportionately reduces lean mass over fat mass, suggesting the need for concurrent strength training to mitigate muscle loss in women following this diet.
摘要：
这项研究调查了生酮低碳水化合物高脂肪（LCHF）饮食对健康人体成分的影响，年轻,体重正常的女性。随着生酮饮食对其各种健康益处的兴趣日益增加，这项研究旨在了解它们对身体成分的影响，关注在此类研究中往往代表性不足的女性。进行交叉设计的随机对照喂养试验，这项研究将生酮LCHF饮食与瑞典国家食品局（NFA）推荐的控制饮食进行了4周的比较。17健康，年轻,正常体重的女性严格遵守所提供的饮食，通过血液β-羟基丁酸酯浓度证实了酮症。双能X射线吸收法（DXA）用于精确的身体成分测量。为了避免偏见，所有统计分析均为盲法.研究结果表明，与对照饮食相比，生酮LCHF饮食导致瘦体重（-1.45kg95％CI：[-1.90;-1.00];p<0.001）和脂肪质量（-0.66kg95％CI：[-1.00;-0.32];p<0.001）显着降低，尽管能量摄入和体力活动水平相似。这项研究得出结论，虽然生酮LCHF饮食对减肥有效，它不成比例地减少了瘦肉量而不是脂肪量，建议需要同时进行力量训练以减轻这种饮食后女性的肌肉损失。
