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Abstract：
The present article describes the synthesis of an isonicotinate-derived meso-arylporphyrin, that has been fully characterized by spectroscopic methods (including fluorescence spectroscopy), as well as elemental analysis and HR-MS. The structure of an n-hexane monosolvate has been determined by single-crystal X-ray diffraction analysis. The radical scavenging activity of this new porphyrin against the 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical has been measured. Its antifungal activity against three yeast strains (C. albicans ATCC 90028, C. glabrata ATCC 64677, and C. tropicalis ATCC 64677) has been tested using the disk diffusion and microdilution methods. Whereas the measured antioxidant activity was low, the porphyrin showed moderate but encouraging antifungal activity. Finally, a study of its effect on the germination of lentil seeds revealed interesting allelopathic properties.
摘要：
本文描述了异烟酸酯衍生的内消旋芳基卟啉的合成，已通过光谱方法（包括荧光光谱法）充分表征，以及元素分析和HR-MS。正己烷单溶剂化物的结构已通过单晶X射线衍射分析确定。已测量了这种新卟啉对2,2-二苯基-1-吡啶酰肼（DPPH）自由基的自由基清除活性。其对三种酵母菌株的抗真菌活性(C.白色念珠菌ATCC90028，光滑念珠菌ATCC64677和热带念珠菌ATCC64677）已使用圆盘扩散和微量稀释方法进行了测试。而测得的抗氧化活性较低，卟啉显示出中等但令人鼓舞的抗真菌活性。最后,对其对扁豆种子萌发的影响的研究揭示了有趣的化感特性。
