RESULTS: Fecal samples from the Bronx MomBa Health Study (Bronx MomBa Health Study) were categorized by delivery mode (vaginal/Cesarean) and analyzed via 16 S rRNA gene sequencing at four timepoints over the first two years of life. Bacteroidota organisms, which have been linked to decreased risk for obesity and type 2 diabetes, were relatively reduced by Cesarean delivery, while Firmicutes organisms were increased. Organisms belonging to the Enterococcus genus, which have been tied to aberrant immune cell development, were relatively increased in the Cesarean delivery microbiomes.
CONCLUSIONS: Due to their far-reaching impact on cardiometabolic and immune functions, Cesarean deliveries in high-risk patient populations should be carefully considered.
结果:BronxMomBa健康研究(BronxMomBa健康研究)的粪便样本按分娩方式(阴道/剖宫产)进行分类,并通过16SrRNA基因测序在前四个时间点进行分析两年的生活。拟杆菌生物,这与肥胖和2型糖尿病的风险降低有关,剖腹产相对减少,而Firmicutes生物增加。属于肠球菌属的生物体,与异常的免疫细胞发育有关,剖宫产微生物组相对增加。
结论:由于它们对心脏代谢和免疫功能的深远影响,应仔细考虑高危患者人群的剖腹产。