■为了确定绿色香蕉粉(GBP)和菠萝纤维粉(PFP)是否促进有益细菌种类,直接改善人类肠道健康,调节肠道微生物组,并了解其作为功能性食品和膳食补充剂的效用。
■超过14天,60名成年人遵循协议要求,完成食品日记和研究问卷,避免食用益生元补充剂,益生菌或益生菌,并摄入含有5克每日总纤维的食物[安慰剂(10.75克),英镑(10.75克)或PFP(7.41克)]。参与者的医疗和基线健康史,以及粪便样本,是在基线时收集的,第7天和第14天。处理粪便DNA用于测序。
■GBP和PFP中的膳食纤维和抗性淀粉(RS)促进了有益细菌的时间增加。GBP显着提高了7种(F。prausnitzii,B.长,B.bifidum,B.青春期,B.假牙,B.obeum,和R.inulinivorans),而PFP富集了6种(B.排卵,B.纤维素,B.bifidum,B.肠肌,R.inulinivorans,和E.siraeum)。这些细菌,发现年轻人有缺陷,由两种粉末促进。PFP受益于16-23岁的男女,而英镑受益于超重/肥胖的个人,包括女性。GBP和PFP纤维和RS通过促进组氨酸改善肠道规律和健康以及代谢,支链氨基酸,短链脂肪酸,和生物素生产。额外的纤维导致\“低\”膨胀和减少\“相当糟糕\”的睡眠中断,不影响睡眠时间。
■补充GBP和PFP会增加有益细菌和代谢产物,改善宿主肠道健康,并提出了增强人类健康的宝贵营养策略。
■AMILI机构审查委员会,标识符2023/0301。
UNASSIGNED: To determine whether green banana powder (GBP) and pineapple fibre powder (PFP) promote beneficial bacterial species, directly improve human gut health and modulate the gut microbiome and understand their utility as functional foods and dietary supplements.
UNASSIGNED: Over 14 days, 60 adults followed protocol requirements, completed food diaries and study questionnaires, avoided consuming supplements with prebiotics, probiotics or postbiotics, and ingested food containing 5 g of total daily fibre [placebo (10.75 g), GBP (10.75 g) or PFP (7.41 g)]. Participants\' medical and baseline wellness histories, as well as stool samples, were collected at baseline, day 7 and 14. Stool DNA was processed for sequencing.
UNASSIGNED: Dietary fibre and resistant starches (RS) in GBP and PFP promoted temporal increases in beneficial bacteria. GBP significantly elevated 7 species (F. prausnitzii, B. longum, B. bifidum, B. adolescentis, B. pseudocatenulatum, B. obeum, and R. inulinivorans), while PFP enriched 6 species (B. ovatus, B. cellulosilyticus, B. bifidum, B. intestinalis, R. inulinivorans, and E. siraeum). These bacteria, found to be deficient in younger adults, were promoted by both powders. PFP benefitted both genders aged 16-23, while GBP benefitted overweight/obese individuals, including females. GBP and PFP fiber and RS improved bowel regularity and health as well as metabolism by promoting histidine, branched-chain amino acids, short-chain fatty acids, and biotin production. The additional fiber caused \"low\" bloatedness and reduced \"fairly bad\" sleep disruptions, without affecting sleep durations.
UNASSIGNED: GBP and PFP supplementation increased beneficial bacteria and metabolites, improved host gut health, and present a valuable nutritional strategy for enhancing human health.
UNASSIGNED: AMILI Institutional Review Board, Identifier 2023/0301.