PDF(Pubmed)
Abstract：
BACKGROUND: Ichthyosis uteri is a rare pathological condition characterized by the replacement of the endometrial lining by stratified squamous epithelium. Yet its occurrence with endometrial adenocarcinoma is very rare.
METHODS: A 68-year-old woman has been experiencing sporadic, minor vaginal hemorrhages for a few months. The gynecological evaluation revealed a uterine enlargement and imaging demonstrated an irregular mass within the uterus.
METHODS: Endometrial adenocarcinoma with transitional cell differentiation; ichthyosis uteri with dysplasia.
METHODS: Radical hysterectomy with pelvic lymphadenectomy was performed followed by postoperative radiotherapy.
RESULTS: Postoperative follow-up at 8 months showed a favorable outcome without signs of recurrence and metastasis.
CONCLUSIONS: Adequate pathological sampling is crucial to identifying the accompanying lesions of ichthyosis uteri. Finding molecular alterations in various pathological morphologies is important to understand the evolution of disease.
METHODS: A 68-year-old woman has been experiencing sporadic, minor vaginal hemorrhages for a few months. The gynecological evaluation revealed a uterine enlargement and imaging demonstrated an irregular mass within the uterus.
METHODS: Endometrial adenocarcinoma with transitional cell differentiation; ichthyosis uteri with dysplasia.
METHODS: Radical hysterectomy with pelvic lymphadenectomy was performed followed by postoperative radiotherapy.
RESULTS: Postoperative follow-up at 8 months showed a favorable outcome without signs of recurrence and metastasis.
CONCLUSIONS: Adequate pathological sampling is crucial to identifying the accompanying lesions of ichthyosis uteri. Finding molecular alterations in various pathological morphologies is important to understand the evolution of disease.
摘要：
背景：子宫鱼鳞病是一种罕见的病理疾病，其特征是分层鳞状上皮取代了子宫内膜。然而，它与子宫内膜腺癌的发生非常罕见。
方法：一名68岁的妇女经历了零星的，阴道轻微出血几个月.妇科评估显示子宫肿大，影像学显示子宫内不规则肿块。
方法：子宫内膜腺癌伴移行细胞分化；子宫鱼鳞病伴发育不良。
方法：行根治性子宫切除术加盆腔淋巴结清扫术，术后放疗。
结果：术后随访8个月，结果良好，无复发和转移迹象。
结论：充分的病理取样对于确定子宫鱼鳞病的伴随病变至关重要。发现各种病理形态中的分子改变对于理解疾病的演变很重要。
方法：一名68岁的妇女经历了零星的，阴道轻微出血几个月.妇科评估显示子宫肿大，影像学显示子宫内不规则肿块。
方法：子宫内膜腺癌伴移行细胞分化；子宫鱼鳞病伴发育不良。
方法：行根治性子宫切除术加盆腔淋巴结清扫术，术后放疗。
结果：术后随访8个月，结果良好，无复发和转移迹象。
结论：充分的病理取样对于确定子宫鱼鳞病的伴随病变至关重要。发现各种病理形态中的分子改变对于理解疾病的演变很重要。
