PDF(Pubmed)
Abstract：
BACKGROUND: Currently, there is no curative treatment for dementia. The implementation of preventive measures is of great importance. Therefore, it is necessary to identify and address individual and modifiable risk factors. Social isolation, defined through social networks, is a factor that may influence the onset and progression of the disease. The networks of older people are mostly composed of either family or friends. The aim of this study is to examine the influence of social isolation and network composition on cognition over the course of 12 months in people with cognitive impairment.
METHODS: Data basis is the multicentre, prospective, longitudinal register study \'Digital Dementia Registery Bavaria-digiDEM Bayern\'. The degree of social isolation was assessed using the Lubben Social Network Scale- Revised (LSNS-R) and the degree of cognitive impairment using the Mini Mental State Examination (MMSE), conducted at baseline and after 12 months. Data were analysed using pre-post ANCOVA, adjusted for baseline MMSE, age, gender, education, living situation and Barthel-Index.
RESULTS: 106 subjects (78.9 ± 8.2 years; 66% female) were included in the analysis. The mean MMSE score at baseline was 24.3 (SD = 3.6). Within the friendship subscore, risk for social isolation was highly prevalent (42.5%). Though, there was no difference between individuals with higher/ lower risk of social isolation within the friendship-network after adjusting for common risk factors in cognitive decline over time, F (1,98) = .046, p = .831, partial η2 = .000.
CONCLUSIONS: The results of this study showed that the risk of social isolation from friends is very high among people with cognitive impairment. However, social isolation does not appear to have a bearing influence on the course of cognition. Nevertheless, it is important for people with cognitive impairment to promote and maintain close social contacts with friends.
METHODS: Data basis is the multicentre, prospective, longitudinal register study \'Digital Dementia Registery Bavaria-digiDEM Bayern\'. The degree of social isolation was assessed using the Lubben Social Network Scale- Revised (LSNS-R) and the degree of cognitive impairment using the Mini Mental State Examination (MMSE), conducted at baseline and after 12 months. Data were analysed using pre-post ANCOVA, adjusted for baseline MMSE, age, gender, education, living situation and Barthel-Index.
RESULTS: 106 subjects (78.9 ± 8.2 years; 66% female) were included in the analysis. The mean MMSE score at baseline was 24.3 (SD = 3.6). Within the friendship subscore, risk for social isolation was highly prevalent (42.5%). Though, there was no difference between individuals with higher/ lower risk of social isolation within the friendship-network after adjusting for common risk factors in cognitive decline over time, F (1,98) = .046, p = .831, partial η2 = .000.
CONCLUSIONS: The results of this study showed that the risk of social isolation from friends is very high among people with cognitive impairment. However, social isolation does not appear to have a bearing influence on the course of cognition. Nevertheless, it is important for people with cognitive impairment to promote and maintain close social contacts with friends.
摘要：
背景：目前，痴呆症没有治愈性治疗方法。预防措施的实施非常重要。因此,有必要识别和解决个人和可修改的风险因素。社会孤立,通过社交网络定义，是可能影响疾病发作和进展的因素。老年人的网络主要由家人或朋友组成。这项研究的目的是研究社会隔离和网络组成对认知功能障碍患者在12个月内的认知的影响。
方法：数据基础是多中心，prospective,纵向登记研究\“数字痴呆症登记巴伐利亚州-拜仁”。使用Lubben社交网络量表（LSNS-R）评估社会隔离程度，并使用迷你精神状态检查（MMSE）评估认知障碍程度，在基线和12个月后进行。使用前-后ANCOVA分析数据，针对基线MMSE进行了调整，年龄,性别,教育,生活状况和Barthel指数。
结果：106名受试者（78.9±8.2岁；66%为女性）被纳入分析。基线时的平均MMSE评分为24.3(SD=3.6)。在友谊子得分中，社会隔离的风险非常普遍(42.5%)。不过,随着时间的推移，在调整认知能力下降的常见风险因素后，友谊网络中社会孤立风险较高/较低的个体之间没有差异，F(1,98)=.046，p=.831，部分η2=.000。
结论：这项研究的结果表明，在认知障碍患者中，与朋友的社交隔离的风险非常高。然而,社会隔离似乎对认知过程没有影响。然而，对于有认知障碍的人来说，促进和保持与朋友的密切社交联系很重要。
方法：数据基础是多中心，prospective,纵向登记研究\“数字痴呆症登记巴伐利亚州-拜仁”。使用Lubben社交网络量表（LSNS-R）评估社会隔离程度，并使用迷你精神状态检查（MMSE）评估认知障碍程度，在基线和12个月后进行。使用前-后ANCOVA分析数据，针对基线MMSE进行了调整，年龄,性别,教育,生活状况和Barthel指数。
结果：106名受试者（78.9±8.2岁；66%为女性）被纳入分析。基线时的平均MMSE评分为24.3(SD=3.6)。在友谊子得分中，社会隔离的风险非常普遍(42.5%)。不过,随着时间的推移，在调整认知能力下降的常见风险因素后，友谊网络中社会孤立风险较高/较低的个体之间没有差异，F(1,98)=.046，p=.831，部分η2=.000。
结论：这项研究的结果表明，在认知障碍患者中，与朋友的社交隔离的风险非常高。然而,社会隔离似乎对认知过程没有影响。然而，对于有认知障碍的人来说，促进和保持与朋友的密切社交联系很重要。
