关键词: ADRD risk Alzheimer’s disease cognitive decline dementia neighborhood sleep

Mesh : Humans Male Female Aged Cognitive Dysfunction / epidemiology psychology Residence Characteristics Sleep Wake Disorders / epidemiology psychology United States / epidemiology Aged, 80 and over Neighborhood Characteristics

来  源:   DOI:10.3233/JAD-240142

Abstract:
UNASSIGNED: Research suggests that the neighborhood in which people live can be a risk or protective factor for various health outcomes, including cognitive decline to Alzheimer\'s disease. Similar to the impact of neighborhood on health outcomes, sleep difficulties have been linked to cognitive function in older adults. However, few studies have examined how neighborhood physical disorders moderate the effects of sleep on subjective cognitive decline (SCD).
UNASSIGNED: The study examined the moderating effect of neighborhood factors on the relationship between sleep difficulties and SCD.
UNASSIGNED: Data were obtained from 2,494 respondents (1,065 males and 1,429 females) from Wave 11 of the National Health and Aging Trends (NHATS) data. Sleep difficulties were operationalized as the presence of difficulties in falling and staying asleep. Neighborhood physical disorder (e.g., vandalism, graffiti) was based on interviewer observations of respondents\' neighborhoods. SCD was operationalized as subjective reports of increasing or worse memory loss in the past 12 months and present memory rating. We utilized Linear regression to test neighborhood physical disorder as a moderator of the relationship between sleep difficulties and SCD.
UNASSIGNED: We found a significant interaction between sleep difficulties and neighborhood physical disorder on SCD (β=0.046, p = 0.031, 95% CI[0.00,0.51], p < 0.001). Participants who reported higher average sleep difficulties and higher levels of neighborhood physical disorder were more likely to report SCD.
UNASSIGNED: Our findings add to inform future health interventions and policy recommendations that address modifiable sources of cognitive decline and risk of Alzheimer\'s disease.
摘要:
研究表明,人们居住的社区可能是各种健康结果的风险或保护因素,包括阿尔茨海默病的认知能力下降。类似于邻里对健康结果的影响,睡眠困难与老年人的认知功能有关.然而,很少有研究研究邻居身体障碍如何缓解睡眠对主观认知能力下降(SCD)的影响.
该研究考察了邻域因素对睡眠困难与SCD之间关系的调节作用。
数据来自第11波国家健康和老龄化趋势(NHATS)数据中的2,494名受访者(1,065名男性和1,429名女性)。睡眠困难被操作为跌倒和保持睡眠困难的存在。邻里生理障碍(例如,故意破坏,涂鸦)是基于采访者对受访者社区的观察。SCD作为过去12个月中记忆丧失增加或恶化的主观报告和目前的记忆评分进行了操作。我们利用线性回归来测试邻域物理障碍,以调节睡眠困难与SCD之间的关系。
我们在SCD上发现了睡眠困难与邻居身体障碍之间的显着相互作用(β=0.03,SE=0.01,95%CI[0.00,0.51],p<0.001)。报告较高的平均睡眠困难和较高水平的邻居身体障碍的参与者更有可能报告SCD。
我们的研究结果为未来的健康干预措施和政策建议提供了信息,以解决认知能力下降和阿尔茨海默病风险的可修改来源。
公众号