Abstract：
UNASSIGNED: Neuropsychiatric symptoms are a robust risk factor for caregiver burden in family dementia caregivers. By grouping these symptoms, clinical interpretations regarding neuropsychiatric symptoms may facilitated because different groups of symptoms may require a different approach for intervention, thereby reducing caregiver burden.
UNASSIGNED: As clustering of neuropsychiatric symptoms could be clinically relevant, we aimed to explore the effects of these clusters on burden in family dementia caregivers.
UNASSIGNED: 152 family dementia caregivers were included. Caregiver burden was measured using the Ervaren Druk door Informele Zorg (EDIZ)/Self-Perceived Pressure from Informal Care, a Dutch questionnaire. Caregivers also reported the neuropsychiatric symptoms and functional impairments in daily activities of the people with dementia they cared for. Multiple regression analyses were used in this cross-sectional study.
UNASSIGNED: Adjusted for functional impairments and sociodemographic variables, neuropsychiatric symptoms were associated with more caregiver burden (p < 0.001). However, this association did not differ between the three neuropsychiatric symptom clusters (p = 0.745).
UNASSIGNED: Neuropsychiatric symptoms were associated with more family caregiver burden, but no conclusive evidence was found that this association differed for the three clusters. Clustering of neuropsychiatric symptoms is, however, worth exploring further in future studies with more participants. If specific links are found, these could be targeted in clinical practice in order to prevent, reduce and/or postpone caregiver burden.
UNASSIGNED: As clustering of neuropsychiatric symptoms could be clinically relevant, we aimed to explore the effects of these clusters on burden in family dementia caregivers.
UNASSIGNED: 152 family dementia caregivers were included. Caregiver burden was measured using the Ervaren Druk door Informele Zorg (EDIZ)/Self-Perceived Pressure from Informal Care, a Dutch questionnaire. Caregivers also reported the neuropsychiatric symptoms and functional impairments in daily activities of the people with dementia they cared for. Multiple regression analyses were used in this cross-sectional study.
UNASSIGNED: Adjusted for functional impairments and sociodemographic variables, neuropsychiatric symptoms were associated with more caregiver burden (p < 0.001). However, this association did not differ between the three neuropsychiatric symptom clusters (p = 0.745).
UNASSIGNED: Neuropsychiatric symptoms were associated with more family caregiver burden, but no conclusive evidence was found that this association differed for the three clusters. Clustering of neuropsychiatric symptoms is, however, worth exploring further in future studies with more participants. If specific links are found, these could be targeted in clinical practice in order to prevent, reduce and/or postpone caregiver burden.
摘要：
■神经精神症状是家庭痴呆症照顾者照顾者负担的重要风险因素。通过对这些症状进行分组，关于神经精神症状的临床解释可能会促进，因为不同的症状组可能需要不同的干预方法，从而减轻照顾者的负担。
■由于神经精神症状的聚集可能与临床相关，我们旨在探讨这些集群对家庭痴呆照顾者负担的影响.
■152名痴呆症家庭照顾者被包括在内。使用ErvarenDruk门InformeleZorg（EDIZ）/非正式护理的自我感觉压力来测量照顾者的负担，荷兰问卷。看护者还报告了他们所照顾的痴呆症患者的日常活动中的神经精神症状和功能障碍。这项横断面研究使用了多元回归分析。
■针对功能损害和社会人口统计学变量进行了调整，神经精神症状与更多的照顾者负担相关(p<0.001).然而,三种神经精神症状群之间的这种关联没有差异(p=0.745).
■神经精神症状与更多的家庭照顾者负担有关，但是没有确凿的证据表明这三个集群的关联不同。神经精神症状的聚类是，然而,值得在未来更多参与者的研究中进一步探索。如果找到特定的链接，这些可以在临床实践中作为目标，以防止，减轻和/或推迟照顾者的负担。
■由于神经精神症状的聚集可能与临床相关，我们旨在探讨这些集群对家庭痴呆照顾者负担的影响.
■152名痴呆症家庭照顾者被包括在内。使用ErvarenDruk门InformeleZorg（EDIZ）/非正式护理的自我感觉压力来测量照顾者的负担，荷兰问卷。看护者还报告了他们所照顾的痴呆症患者的日常活动中的神经精神症状和功能障碍。这项横断面研究使用了多元回归分析。
■针对功能损害和社会人口统计学变量进行了调整，神经精神症状与更多的照顾者负担相关(p<0.001).然而,三种神经精神症状群之间的这种关联没有差异(p=0.745).
■神经精神症状与更多的家庭照顾者负担有关，但是没有确凿的证据表明这三个集群的关联不同。神经精神症状的聚类是，然而,值得在未来更多参与者的研究中进一步探索。如果找到特定的链接，这些可以在临床实践中作为目标，以防止，减轻和/或推迟照顾者的负担。
