METHODS: Here, we present three cases of sarcoidosis with unusual organ involvement and biopsy findings of necrosis, leading to a delay in diagnosis and treatment. Case 1 was presented with lymphoreticular involvement within the intraparotid lymph node and genitourinary area. Biopsy from the epididymis showed necrosis, initially leading to treatment for tuberculosis (TB). Case 2 describes lymphoreticular involvement and cardiac symptoms. His cervical and bone marrow biopsies showed necrosis. Case 3\'s presentation was disseminated lymphadenopathy with hepatosplenomegaly, initially suspected as malignancy or TB.
CONCLUSIONS: While biopsy plays a significant role in diagnosing sarcoidosis, the presence of necrosis alone should not lead to its exclusion.
方法:这里,我们介绍了三例结节病与异常器官受累和坏死活检结果,导致诊断和治疗的延误。病例1表现为颈动脉内淋巴结和泌尿生殖道区域的淋巴网状受累。附睾活检显示坏死,最初导致结核病(TB)的治疗。病例2描述了淋巴网状受累和心脏症状。他的宫颈和骨髓活检显示坏死。病例3表现为播散性淋巴结肿大伴肝脾肿大,最初怀疑为恶性肿瘤或结核病。
结论:虽然活检在结节病的诊断中起着重要作用,单独坏死的存在不应导致其排除。