Abstract：
Research into innovative non-pharmacological therapeutic routes via the utilization of natural elements like zinc (Zn) has been motivated by the discovery of new severe acute respiratory syndrome-related coronavirus 2 (SARS-COV2) variants and the ineffectiveness of certain vaccination treatments during COVID-19 pandemic. In addition, research on SARS-COV-2\'s viral cellular entry and infection mechanism has shown that it may seriously harm reproductive system cells and impair testicular function in young men and adolescents, which may lead to male infertility over time. In this context, we conducted a narrative review to give an overview of the data pertaining to Zn\'s critical role in testicular tissue, the therapeutic use of such micronutrients to enhance male fertility, as well as in the potential mitigation of COVID-19, with the ultimate goal of elucidating the hypothesis of the potential use of Zn supplements to prevent the possible harmful effects of SARS-COV2 infection on testis physiological function, and subsequently, on male fertility.
摘要：
通过利用锌（Zn）等天然元素对创新的非药物治疗途径进行研究的动机是发现了新的严重急性呼吸综合征相关冠状病毒2（SARS-COV2）变体以及某些疫苗接种治疗在COVID-19大流行期间无效。此外,对SARS-COV-2病毒进入细胞和感染机制的研究表明，它可能严重危害年轻男性和青少年的生殖系统细胞并损害睾丸功能，随着时间的推移，这可能会导致男性不育。在这种情况下，我们进行了叙述性审查，以概述有关锌在睾丸组织中的关键作用的数据，这种微量营养素的治疗用途，以提高男性的生育能力，以及在COVID-19的潜在缓解中，最终目标是阐明潜在使用锌补充剂来预防SARS-COV2感染对睾丸生理功能可能产生的有害影响的假设，随后,关于男性生育能力。
