PDF(Pubmed)
Abstract：
The recent COVID-19 pandemic has raised interest in efficient air disinfection solutions. The application of germicidal ultraviolet (GUV) irradiation is an excellent contender to prevent airborne transmission of COVID-19, as well as other existing and future infectious airborne diseases. While GUV has already been proven effective in inactivating SARS-CoV-2, quantitative data on UV susceptibility and dose requirements, needed to predict and optimize the performance of GUV solutions, is still limited. In this study, the UV susceptibility of aerosolized SARS-CoV-2 to 254 nm ultraviolet (UV) irradiation is investigated. This is done by employing 3D computational fluid dynamics based simulations of SARS-CoV-2 inactivation in a test chamber equipped with an upper-room UV-C luminaire and comparing the results to previously published measurements performed in the same test chamber. The UV susceptibility found in this study is (0.6 ± 0.2) m2/J, which is equivalent to a D90 dose between 3 and 6 J/m2. These values are in the same range as previous estimations based on other corona viruses and inactivation data reported in literature.
摘要：
最近的COVID-19大流行引起了人们对有效空气消毒解决方案的兴趣。杀菌紫外线（GUV）辐射的应用是防止COVID-19空气传播以及其他现有和未来传染性空气传播疾病的绝佳竞争者。虽然GUV已被证明可有效灭活SARS-CoV-2，但有关紫外线敏感性和剂量要求的定量数据，需要预测和优化GUV解决方案的性能，仍然有限。在这项研究中,研究了雾化SARS-CoV-2对254nm紫外线（UV）辐射的紫外线敏感性。这是通过在配备有上层UV-C照明器的测试室中采用基于3D计算流体动力学的SARS-CoV-2灭活模拟并将结果与在同一测试室中执行的先前发布的测量进行比较来完成的。在这项研究中发现的紫外线敏感性为（0.6±0.2）m2/J，这相当于在3和6J/m2之间的D90剂量。这些值与基于文献中报道的其他电晕病毒和灭活数据的先前估计在相同的范围内。
