PDF(Pubmed)
Abstract：
The slender shape of axons makes them uniquely susceptible to mechanical stress. In this issue, Pan, Hu et al. (https://doi.org/10.1083/jcb.202206046) use a microfluidic axon-on-chip device to reveal how actomyosin protects axons from mild mechanical stress, by transiently adopting a beaded shape that helps limit the spread of damaging calcium waves.
摘要：
轴突的细长形状使它们特别容易受到机械应力的影响。在这个问题上，Pan,胡等人。（https://doi.org/10.1083/jcb.202206046）使用微流控芯片轴突设备来揭示肌动球蛋白如何保护轴突免受轻度机械应力，暂时采用串珠形状，有助于限制破坏性钙波的传播。
