{Reference Type}: Journal Article {Title}: Stress balls for the brain: How beading protects axons from mechanical damage. {Author}: Leterrier C; {Journal}: J Cell Biol {Volume}: 223 {Issue}: 8 {Year}: 2024 Aug 5 {Factor}: 8.077 {DOI}: 10.1083/jcb.202407024 {Abstract}: The slender shape of axons makes them uniquely susceptible to mechanical stress. In this issue, Pan, Hu et al. (https://doi.org/10.1083/jcb.202206046) use a microfluidic axon-on-chip device to reveal how actomyosin protects axons from mild mechanical stress, by transiently adopting a beaded shape that helps limit the spread of damaging calcium waves.