Abstract：
UNASSIGNED: Diabetes Mellitus is a chronic disease characterized by uncontrolled blood sugar levels, which lead to end-organ damage. While the diagnosis and treatment of its complications have been extensively studied, the effect of Hyperbaric Oxygen Therapy (HBO2) on diabetes-related oral complications remains unexplored.
UNASSIGNED: This prospective clinical study aims to investigate the effect of HBO2 on diabetes-related oral complications.
UNASSIGNED: Twenty patients diagnosed with diabetic foot ulcers and scheduled for HBO2 were included in this study. We recorded stimulated and unstimulated saliva pH, buffering capacity, flow rate, and subjective symptoms such as dry mouth, halitosis, taste loss, difficulty swallowing, and clinical examination findings before HBO2 and after the 21st session.
UNASSIGNED: Upon comparing the findings, we observed a significant decrease in dry mouth and halitosis, periodontal disease severity, and healing of candida-related stomatitis and angular cheilitis. Despite not reaching statistical significance for other saliva parameters, the unstimulated salivary flow rate increased to normal limits (0.3-0.4 ml/min) in 6 out of 8 patients with a flow rate of less than 0.25 ml/min.
UNASSIGNED: Our study investigated the effect of HBO2 on diabetes-related oral complications for the first time, highlighting symptomatic relief for dry mouth and halitosis. Although our results are insufficient to report a definitive benefit, they underscore the need for further research on the oral health effects of HBO2.
UNASSIGNED: This prospective clinical study aims to investigate the effect of HBO2 on diabetes-related oral complications.
UNASSIGNED: Twenty patients diagnosed with diabetic foot ulcers and scheduled for HBO2 were included in this study. We recorded stimulated and unstimulated saliva pH, buffering capacity, flow rate, and subjective symptoms such as dry mouth, halitosis, taste loss, difficulty swallowing, and clinical examination findings before HBO2 and after the 21st session.
UNASSIGNED: Upon comparing the findings, we observed a significant decrease in dry mouth and halitosis, periodontal disease severity, and healing of candida-related stomatitis and angular cheilitis. Despite not reaching statistical significance for other saliva parameters, the unstimulated salivary flow rate increased to normal limits (0.3-0.4 ml/min) in 6 out of 8 patients with a flow rate of less than 0.25 ml/min.
UNASSIGNED: Our study investigated the effect of HBO2 on diabetes-related oral complications for the first time, highlighting symptomatic relief for dry mouth and halitosis. Although our results are insufficient to report a definitive benefit, they underscore the need for further research on the oral health effects of HBO2.
摘要：
■糖尿病是一种以血糖水平失控为特征的慢性疾病，导致终末器官损伤。虽然其并发症的诊断和治疗已被广泛研究，高压氧治疗(HBO2)对糖尿病相关口腔并发症的疗效尚待研究.
■这项前瞻性临床研究旨在研究HBO2对糖尿病相关口腔并发症的影响。
■本研究包括20例诊断为糖尿病足溃疡并计划进行HBO2治疗的患者。我们记录了刺激和未刺激的唾液pH值，缓冲能力,流量,和主观症状，如口干，口臭,味觉丧失,吞咽困难,以及HBO2之前和第21届会议之后的临床检查结果。
■比较调查结果后，我们观察到口干和口臭显著减少，牙周病的严重程度，念珠菌相关性口腔炎和唇角炎的愈合。尽管其他唾液参数没有达到统计学意义，在8例患者中,有6例患者的未刺激唾液流速增加至正常范围(0.3-0.4ml/min),其流速小于0.25ml/min.
■我们的研究首次调查了HBO2对糖尿病相关口腔并发症的影响，强调口干和口臭的症状缓解。尽管我们的结果不足以报告最终的益处，他们强调需要进一步研究HBO2对口腔健康的影响.
■这项前瞻性临床研究旨在研究HBO2对糖尿病相关口腔并发症的影响。
■本研究包括20例诊断为糖尿病足溃疡并计划进行HBO2治疗的患者。我们记录了刺激和未刺激的唾液pH值，缓冲能力,流量,和主观症状，如口干，口臭,味觉丧失,吞咽困难,以及HBO2之前和第21届会议之后的临床检查结果。
■比较调查结果后，我们观察到口干和口臭显著减少，牙周病的严重程度，念珠菌相关性口腔炎和唇角炎的愈合。尽管其他唾液参数没有达到统计学意义，在8例患者中,有6例患者的未刺激唾液流速增加至正常范围(0.3-0.4ml/min),其流速小于0.25ml/min.
■我们的研究首次调查了HBO2对糖尿病相关口腔并发症的影响，强调口干和口臭的症状缓解。尽管我们的结果不足以报告最终的益处，他们强调需要进一步研究HBO2对口腔健康的影响.
