Abstract：
BACKGROUND: During COVID-19 pandemic, cleaning/disinfection activities were highly recommended. This study summarizes the state of art and estimates the prevalence of dangerous exposures to specific chemicals managed by Poison Centers (PCs) from all over the world during 2020 vs 2019, trying to overcome the critical aspects of the product categorization systems used by PCs.
METHODS: A systematic research was conducted in 3 major databases and 2 websites of PCs associations. Proportional meta-analyses were performed to estimate the prevalence of exposures to disinfectants, household products and hand sanitizers in 2020 vs 2019.
RESULTS: The pooled prevalence of exposures to disinfectants, household products and hand sanitizers were respectively 5.9% (95% CI 4.9-7.0) (2019: 4.4% vs 2020: 7.8%; p=0.22), 25.9% (95% CI 24.0-27.7) (2019: 25.0% vs 2020: 28.6%; p=0.71) and 1.6% (95% CI 1.3-1.9) (2019: 0.6% vs 2020: 2.8%; p<0.001).
CONCLUSIONS: This study detected overall increases of exposures to specific chemicals in 2020, suggesting that the awareness on topics related to the safe use of these products should be improved, especially during health emergencies, highlighting the need to develop standardized systems to better compare data coming from PCs all over the world.
METHODS: A systematic research was conducted in 3 major databases and 2 websites of PCs associations. Proportional meta-analyses were performed to estimate the prevalence of exposures to disinfectants, household products and hand sanitizers in 2020 vs 2019.
RESULTS: The pooled prevalence of exposures to disinfectants, household products and hand sanitizers were respectively 5.9% (95% CI 4.9-7.0) (2019: 4.4% vs 2020: 7.8%; p=0.22), 25.9% (95% CI 24.0-27.7) (2019: 25.0% vs 2020: 28.6%; p=0.71) and 1.6% (95% CI 1.3-1.9) (2019: 0.6% vs 2020: 2.8%; p<0.001).
CONCLUSIONS: This study detected overall increases of exposures to specific chemicals in 2020, suggesting that the awareness on topics related to the safe use of these products should be improved, especially during health emergencies, highlighting the need to develop standardized systems to better compare data coming from PCs all over the world.
摘要：
背景：在COVID-19大流行期间，强烈建议进行清洁/消毒活动。这项研究总结了最新技术，并估计了2020年与2019年期间来自世界各地的毒物中心（PC）管理的特定化学物质的危险暴露率，试图克服PC使用的产品分类系统的关键方面。
方法：在3个主要数据库和2个PC协会网站中进行了系统研究。进行了比例荟萃分析，以估计暴露于消毒剂的患病率，2020年家用产品和洗手液与2019年相比。
结果：暴露于消毒剂的总患病率，家用产品和洗手液分别为5.9%（95%CI4.9-7.0）（2019年：4.4%vs2020年：7.8%；p=0.22），25.9%（95%CI24.0-27.7）（2019年：25.0%vs2020年：28.6%；p=0.71）和1.6%（95%CI1.3-1.9）（2019年：0.6%vs2020年：2.8%；p<0.001）。
结论：这项研究发现，在2020年，对特定化学品的暴露量总体上有所增加，这表明应提高对与安全使用这些产品有关的主题的认识。尤其是在突发卫生事件期间，强调需要开发标准化系统，以更好地比较来自世界各地PC的数据。
方法：在3个主要数据库和2个PC协会网站中进行了系统研究。进行了比例荟萃分析，以估计暴露于消毒剂的患病率，2020年家用产品和洗手液与2019年相比。
结果：暴露于消毒剂的总患病率，家用产品和洗手液分别为5.9%（95%CI4.9-7.0）（2019年：4.4%vs2020年：7.8%；p=0.22），25.9%（95%CI24.0-27.7）（2019年：25.0%vs2020年：28.6%；p=0.71）和1.6%（95%CI1.3-1.9）（2019年：0.6%vs2020年：2.8%；p<0.001）。
结论：这项研究发现，在2020年，对特定化学品的暴露量总体上有所增加，这表明应提高对与安全使用这些产品有关的主题的认识。尤其是在突发卫生事件期间，强调需要开发标准化系统，以更好地比较来自世界各地PC的数据。
