Mesh : Animals Caenorhabditis elegans / genetics Germ Cells / metabolism Developmental Biology / history History, 21st Century History, 20th Century Humans RNA, Messenger / genetics metabolism Caenorhabditis elegans Proteins / metabolism genetics

来  源:   DOI:10.1242/dev.204215

Abstract:
Germ granules have been hypothesized to deliver mRNAs of germ cell fate determinants to primordial germ cells. Now, a new study in Development finds that many mRNAs enriched in germ granules are not involved in germline development in Caenorhabditis elegans. To find out more about the story behind the paper, we caught up with first author Alyshia Scholl, second author Yihong Liu and corresponding author Geraldine Seydoux, Professor at Johns Hopkins University School of Medicine.
摘要:
已经假设胚芽颗粒将生殖细胞命运决定子的mRNA递送至原始生殖细胞。现在,一项新的研究发现,许多富含胚芽颗粒的mRNAs不参与秀丽隐杆线虫的种系发育。为了了解更多关于报纸背后的故事,我们赶上了第一作者AlyshiaScholl,第二作者刘一红和通讯作者GeraldineSeydoux,约翰霍普金斯大学医学院教授。
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