PDF(Pubmed)
Abstract：
The global impact of drug shortages on healthcare systems is a concerning issue that needs urgent attention. These shortages not only jeopardize patient care, public health, and healthcare delivery but also pose distinct challenges for pediatric populations due to their specific medication requirements and vulnerabilities. It is imperative to address this issue to safeguard the health and wellbeing of this specific age group. This review Gaimed to conduct a systematic analysis of strategies for addressing drug shortages in pediatric care from 2014 to 2024. The search included five databases: PubMed, Reaxys, Embase, Scopus, and Science Direct, using the keywords \"drug shortage\" and \"pediatric\". The final protocol was developed following the guidelines outlined in the \" The PRISMA 2020 statement: An updated guideline for reporting systematic reviews\". In total, 234 publications were identified. After screening the search results and applying inclusion and exclusion measures, a total of 27 original research papers were included. The primary finding indicates that a comprehensive approach rooted in risk management can significantly mitigate drug shortages in pediatric settings. This approach should address underlying causes such as manufacturer and delivery challenges and focus on prevention through enhanced forecasting and vigilant shortage monitoring. The most prevalent response involved seeking alternative treatment options. It is imperative to implement institutional and national guidelines, foster communication, and provider education, and minimize waste to effectively mitigate drug shortages in pediatric settings.
摘要：
药物短缺对医疗保健系统的全球影响是一个需要紧急关注的问题。这些短缺不仅危及病人的护理，公共卫生,但由于儿科人群的特定药物要求和脆弱性，也给他们带来了明显的挑战。必须解决这一问题，以保障这一特定年龄组的健康和福祉。这篇综述旨在对2014年至2024年儿科护理中解决药物短缺的策略进行系统分析。搜索包括五个数据库：PubMed，Reaxys,Embase,Scopus,和科学直接，使用关键字“药物短缺”和“儿科”。最终方案是根据“PRISMA2020声明：报告系统审查的更新指南”中概述的指南制定的。总的来说,已确定234种出版物。在筛选搜索结果并应用纳入和排除措施后，共纳入27篇原创研究论文。主要发现表明，植根于风险管理的综合方法可以显着减轻儿科环境中的药物短缺。这种方法应解决潜在的原因，如制造商和交货方面的挑战，并通过加强预测和警惕的短缺监测来注重预防。最普遍的反应涉及寻求替代治疗方案。必须落实体制和国家准则,促进沟通，和提供者教育，并尽量减少浪费，以有效缓解儿科环境中的药物短缺。
