PDF(Pubmed)
Abstract：
BACKGROUND: Extraskeletal osteosarcoma is an extremely rare malignancy that accounts for 1% of soft tissue sarcoma and 4.3% of all osteosarcoma. Extraskeletal osteosarcoma can develop in a patient between the ages of 48 and 60 years. The incidence of extraskeletal osteosarcoma is slightly higher in male patients than in females.
METHODS: A 50-year-old Caucasian male patient presented with a 6-month history of intermittent lower-left back pain that limits his activity. Prior ultrasonography and abdominal computed tomography scan showed a diagnosis of kidney stone and tumor in the lower-left abdomen. The computed tomography urography with contrast revealed a mass suspected as a left retroperitoneal malignant tumor. Hence, the tumor was resected through laparotomy and the patient continued with histopathological and immunohistochemistry examination with the result of extraskeletal osteosarcoma.
CONCLUSIONS: Extraskeletal osteosarcoma presents diagnostic challenges requiring multimodal examination, including histological and immunohistochemistry analyses. This case underscores the aggressive nature and poor prognosis despite undergoing the current suggested treatment.
METHODS: A 50-year-old Caucasian male patient presented with a 6-month history of intermittent lower-left back pain that limits his activity. Prior ultrasonography and abdominal computed tomography scan showed a diagnosis of kidney stone and tumor in the lower-left abdomen. The computed tomography urography with contrast revealed a mass suspected as a left retroperitoneal malignant tumor. Hence, the tumor was resected through laparotomy and the patient continued with histopathological and immunohistochemistry examination with the result of extraskeletal osteosarcoma.
CONCLUSIONS: Extraskeletal osteosarcoma presents diagnostic challenges requiring multimodal examination, including histological and immunohistochemistry analyses. This case underscores the aggressive nature and poor prognosis despite undergoing the current suggested treatment.
摘要：
背景：骨外骨肉瘤是一种极其罕见的恶性肿瘤，占软组织肉瘤的1％和所有骨肉瘤的4.3％。骨外骨肉瘤可以在年龄在48至60岁之间的患者中发展。男性患者的骨外骨肉瘤的发生率略高于女性。
方法：一名50岁的白种人男性患者，有6个月的间歇性左下背部疼痛病史，这限制了他的活动。先前的超声检查和腹部计算机断层扫描显示诊断为左下腹部的肾结石和肿瘤。计算机断层扫描尿路造影显示怀疑为左腹膜后恶性肿瘤的肿块。因此，通过剖腹手术切除肿瘤，患者继续进行组织病理学和免疫组织化学检查，结果为骨外骨肉瘤。
结论：骨外骨肉瘤提出了需要多模式检查的诊断挑战，包括组织学和免疫组织化学分析。尽管接受了当前建议的治疗，但该病例强调了侵袭性和不良预后。
方法：一名50岁的白种人男性患者，有6个月的间歇性左下背部疼痛病史，这限制了他的活动。先前的超声检查和腹部计算机断层扫描显示诊断为左下腹部的肾结石和肿瘤。计算机断层扫描尿路造影显示怀疑为左腹膜后恶性肿瘤的肿块。因此，通过剖腹手术切除肿瘤，患者继续进行组织病理学和免疫组织化学检查，结果为骨外骨肉瘤。
结论：骨外骨肉瘤提出了需要多模式检查的诊断挑战，包括组织学和免疫组织化学分析。尽管接受了当前建议的治疗，但该病例强调了侵袭性和不良预后。
