{Reference Type}: Case Reports {Title}: Extraskeletal osteosarcoma infiltrating pancreas, spleen, gastric, and left kidney: a case report. {Author}: Jeo WS;Christina S;Zacharia NJ;Razi K; {Journal}: J Med Case Rep {Volume}: 18 {Issue}: 1 {Year}: 2024 Jul 10 暂无{DOI}: 10.1186/s13256-024-04608-x {Abstract}: BACKGROUND: Extraskeletal osteosarcoma is an extremely rare malignancy that accounts for 1% of soft tissue sarcoma and 4.3% of all osteosarcoma. Extraskeletal osteosarcoma can develop in a patient between the ages of 48 and 60 years. The incidence of extraskeletal osteosarcoma is slightly higher in male patients than in females.
METHODS: A 50-year-old Caucasian male patient presented with a 6-month history of intermittent lower-left back pain that limits his activity. Prior ultrasonography and abdominal computed tomography scan showed a diagnosis of kidney stone and tumor in the lower-left abdomen. The computed tomography urography with contrast revealed a mass suspected as a left retroperitoneal malignant tumor. Hence, the tumor was resected through laparotomy and the patient continued with histopathological and immunohistochemistry examination with the result of extraskeletal osteosarcoma.
CONCLUSIONS: Extraskeletal osteosarcoma presents diagnostic challenges requiring multimodal examination, including histological and immunohistochemistry analyses. This case underscores the aggressive nature and poor prognosis despite undergoing the current suggested treatment.