METHODS: The SHOW study follows a measurement burst design that includes 3, 7-day data collection bursts (baseline, 6-month and 12-month follow-ups). Sleep is measured with three methods: sleep diary, actigraphy and polysomnography. Energy balance over 7 days is based on resting and postprandial energy expenditure measured via indirect calorimetry, physical activity via accelerometry and self-reported and ad libitum energy intake methods. Self-reported methods and blood biomarkers assess fasting and postprandial appetite profiles and a behavioural-choice task measures food reward. Cortisol awakening response and diurnal cortisol profiles over 3 days are assessed via saliva samples and chronic cortisol exposure via a hair sample. Hydration markers are assessed with 24-hour urine collection over 3 days and fasting blood biomarkers. Race-related stress is self-reported over 7 days. Home and neighbourhood environments (via the Windshield Survey) is observer assessed.
BACKGROUND: Ethics approval was granted by the University of North Carolina at Greensboro\'s Institutional Review Board. Study findings will be disseminated through peer-reviewed publications, presentations at scientific meetings and reports, briefs/infographics for lay and community audiences.
方法:SHOW研究遵循测量突发设计,其中包括3、7天的数据收集突发(基线,6个月和12个月的随访)。用三种方法测量睡眠:睡眠日记,活动图和多导睡眠图。7天的能量平衡基于通过间接量热法测量的静息和餐后能量消耗,通过加速度测量和自我报告和随意摄入能量的方法进行身体活动。自我报告的方法和血液生物标志物评估空腹和餐后食欲概况,行为选择任务衡量食物奖励。通过唾液样品和通过毛发样品的慢性皮质醇暴露评估3天的皮质醇觉醒反应和昼夜皮质醇谱。用3天的24小时尿液收集和空腹血液生物标志物来评估水合标志物。与种族相关的压力在7天内自我报告。家庭和邻里环境(通过挡风玻璃测量)由观察者评估。
背景:伦理批准是由北卡罗来纳大学格林斯伯勒大学的机构审查委员会批准的。研究结果将通过同行评审的出版物传播,在科学会议和报告中的演讲,为外行和社区观众提供的简报/信息图表。