Mesh : Humans Female Bevacizumab / administration & dosage Retinal Perforations / diagnosis etiology drug therapy Middle Aged Intravitreal Injections Angiogenesis Inhibitors / administration & dosage Tomography, Optical Coherence / methods Visual Acuity Epiretinal Membrane / diagnosis Vascular Endothelial Growth Factor A / antagonists & inhibitors

来  源:   DOI:10.3126/nepjoph.v15i2.55033

Abstract:
BACKGROUND: Aetiology for non-closure of full-thickness macular hole (FTMH) becomes crucial in determining the method of effective mode of intervention. Association of epiretinal proliferation (ERP) along with full-thickness macular hole (FTMH) have shown poorer anatomic and visual outcomes after surgical intervention. Various surgical techniques have been described in literature for treatment of persistent MH.
METHODS: We report a A 60-year-old female patient with FTMH secondary to branched retinal vein occlusion (BRVO) initially associated with ERP.
METHODS: She was successfully managed by treating with combination of intravitreal injection of off label bevacizumab (Avastin) (1.25 mg/0.05 ml) and pure gas of SF6 (1 cc) under topical anaesthesia after an initial surgical intervention.
CONCLUSIONS: Presence of ERP in retinal vein occlusion cases needs closer and frequent follow up. IVB can be used as an adjunct in treating secondary MH.
摘要:
背景:全厚度黄斑裂孔(FTMH)非闭合的病因在确定有效干预方式方面至关重要。视网膜上增生(ERP)与全厚度黄斑裂孔(FTMH)的关联在手术干预后显示出较差的解剖和视觉结果。文献中已经描述了用于治疗持续性MH的各种外科技术。
方法:我们报告了一名60岁的女性FTMH患者,继发于视网膜分支静脉阻塞(BRVO),最初与ERP相关。
方法:在初次手术干预后,在局部麻醉下,玻璃体内注射脱标贝伐单抗(阿瓦斯汀)(1.25mg/0.05ml)和SF6纯气体(1cc)联合治疗,成功治疗。
结论:视网膜静脉阻塞病例中存在ERP需要密切和频繁的随访。IVB可用作治疗继发性MH的辅助手段。
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