Abstract：
Infants at risk of HIE require early identification and initiation of therapeutic hypothermia (TH). Earlier treatment with TH is associated with better outcomes. aEEG is frequently used when making the decision whether to commence TH. As this is often limited to tertiary centers, TH may be delayed if the infant requires transport to a center that provides it. We aimed to provide a method for the application of amplitude-integrated electroencephalogram (aEEG) and to determine the feasibility of acquiring clinically meaningful information during transport. All infants ≥35 weeks, at risk of HIE at referral, were eligible for inclusion. Scalp electrodes were placed in the C3-C4; P3-P4 position on the infant\'s scalp and connected to the aEEG amplifier. The aEEG amplifier was, in turn, connected to a clinical tablet computer with EEG software to collect and analyze aEEG information. Recordings were reviewed by the chief principal investigator and two independent reviewers (blinded) for background trace and artifact. Predefined criteria for data quality were set to movement artifacts and software impedance notifications. Surveys were completed by healthcare staff and parents for acceptability and ease of use.
摘要：
有HIE风险的婴儿需要早期识别并开始治疗性低温（TH）。早期治疗与更好的结果相关。脑电图是经常使用时作出的决定是否开始TH。由于这通常仅限于三级中心，如果婴儿需要运输到提供TH的中心，则TH可能会延迟。我们旨在提供一种应用振幅整合脑电图（aEEG）的方法，并确定在运输过程中获取有临床意义的信息的可行性。所有≥35周的婴儿，转诊时有HIE的风险，有资格列入。头皮电极放置在婴儿头皮的C3-C4；P3-P4位置，并连接到aEEG放大器。aEEG放大器是，反过来,连接到临床平板电脑与脑电图软件收集和分析aEEG信息。首席首席研究员和两名独立审稿人（蒙蔽）对记录进行了审查，以了解背景痕迹和人工制品。数据质量的预定义标准设置为运动伪影和软件阻抗通知。医护人员和家长完成了调查，以确保可接受性和易用性。
