PDF(Pubmed)
Abstract：
UNASSIGNED: This study aims to develop a novel MRI-based paravertebral muscle quality (PVMQ) score for assessing muscle quality and to investigate its correlation with the degree of fat infiltration (DFF) and the vertebral bone quality (VBQ) score of paravertebral muscles. Additionally, the study compares the effectiveness of the PVMQ score and the VBQ score in assessing muscle quality and bone quality.
UNASSIGNED: PVMQ scores were derived from the ratio of paravertebral muscle signal intensity (SI) to L3 cerebrospinal fluid SI on T2-weighted MRI. Image J software assessed paravertebral muscle cross-sectional area (CSA) and DFF. Spearman rank correlation analyses explored associations between PVMQ, VBQ scores, DFF, and T-scores in both genders. Receiver operating characteristic (ROC) curves compared PVMQ and VBQ scores\' effectiveness in distinguishing osteopenia/osteoporosis and high paraspinal muscle DFF.
UNASSIGNED: In this study of 144 patients (94 females), PVMQ scores were significantly higher in osteoporosis and osteopenia groups compared to normals, with variations observed between genders (P < 0.05). PVMQ showed stronger positive correlation with VBQ scores and DFF in females than males (0.584 vs 0.445, 0.579 vs 0.528; P < 0.01). ROC analysis favored PVMQ over VBQ for low muscle mass in both genders (AUC = 0.767 vs 0.718, 0.793 vs 0.718). VBQ was better for bone mass in males (0.737/0.865 vs 0.691/0.858), whereas PVMQ excelled for females (0.808/0.764 vs 0.721/0.718).
UNASSIGNED: The novel PVMQ score provides a reliable assessment of paravertebral muscle quality and shows a strong correlation with VBQ scores and DFF, particularly in females. It outperforms VBQ scores in evaluating muscle mass and offers valuable insights for assessing bone mass in females. These findings underscore the potential of the PVMQ score as a dual-purpose tool for evaluating both muscle and bone health, informing future research and clinical practice.
UNASSIGNED: PVMQ scores were derived from the ratio of paravertebral muscle signal intensity (SI) to L3 cerebrospinal fluid SI on T2-weighted MRI. Image J software assessed paravertebral muscle cross-sectional area (CSA) and DFF. Spearman rank correlation analyses explored associations between PVMQ, VBQ scores, DFF, and T-scores in both genders. Receiver operating characteristic (ROC) curves compared PVMQ and VBQ scores\' effectiveness in distinguishing osteopenia/osteoporosis and high paraspinal muscle DFF.
UNASSIGNED: In this study of 144 patients (94 females), PVMQ scores were significantly higher in osteoporosis and osteopenia groups compared to normals, with variations observed between genders (P < 0.05). PVMQ showed stronger positive correlation with VBQ scores and DFF in females than males (0.584 vs 0.445, 0.579 vs 0.528; P < 0.01). ROC analysis favored PVMQ over VBQ for low muscle mass in both genders (AUC = 0.767 vs 0.718, 0.793 vs 0.718). VBQ was better for bone mass in males (0.737/0.865 vs 0.691/0.858), whereas PVMQ excelled for females (0.808/0.764 vs 0.721/0.718).
UNASSIGNED: The novel PVMQ score provides a reliable assessment of paravertebral muscle quality and shows a strong correlation with VBQ scores and DFF, particularly in females. It outperforms VBQ scores in evaluating muscle mass and offers valuable insights for assessing bone mass in females. These findings underscore the potential of the PVMQ score as a dual-purpose tool for evaluating both muscle and bone health, informing future research and clinical practice.
摘要：
■本研究旨在开发一种基于MRI的新型椎旁肌肉质量（PVMQ）评分，用于评估肌肉质量，并研究其与脂肪浸润程度（DFF）和椎旁肌肉的椎骨质量（VBQ）评分的相关性。此外,本研究比较了PVMQ评分和VBQ评分在评估肌肉质量和骨质量方面的有效性.
■PVMQ评分是根据T2加权MRI上椎旁肌信号强度（SI）与L3脑脊液SI的比值得出的。图像J软件评估椎旁肌肉横截面积(CSA)和DFF。Spearman等级相关分析探讨了PVMQ，VBQ分数,DFF,和两种性别的T分数。受试者工作特征（ROC）曲线比较了PVMQ和VBQ评分在区分骨质减少/骨质疏松和高椎旁肌DFF方面的有效性。
■在这项144名患者（94名女性）的研究中，与正常人相比，骨质疏松症和骨量减少组的PVMQ评分明显更高，性别间存在差异(P<0.05)。女性PVMQ与VBQ评分和DFF呈显著正相关(0.584vs0.445,0.579vs0.528,P<0.01)。对于两种性别的低肌肉质量，ROC分析更青睐PVMQ而不是VBQ（AUC=0.767vs0.718，0.793vs0.718）。VBQ对男性骨量较好（0.737/0.865vs0.691/0.858），而PVMQ在女性中表现优异（0.808/0.764vs0.721/0.718）。
■新的PVMQ评分对椎旁肌肉质量提供了可靠的评估，并显示出与VBQ评分和DFF的强相关性，尤其是女性。它在评估肌肉质量方面优于VBQ评分，并为评估女性骨骼质量提供了有价值的见解。这些发现强调了PVMQ评分作为评估肌肉和骨骼健康的双重目的工具的潜力。为未来的研究和临床实践提供信息。
■PVMQ评分是根据T2加权MRI上椎旁肌信号强度（SI）与L3脑脊液SI的比值得出的。图像J软件评估椎旁肌肉横截面积(CSA)和DFF。Spearman等级相关分析探讨了PVMQ，VBQ分数,DFF,和两种性别的T分数。受试者工作特征（ROC）曲线比较了PVMQ和VBQ评分在区分骨质减少/骨质疏松和高椎旁肌DFF方面的有效性。
■在这项144名患者（94名女性）的研究中，与正常人相比，骨质疏松症和骨量减少组的PVMQ评分明显更高，性别间存在差异(P<0.05)。女性PVMQ与VBQ评分和DFF呈显著正相关(0.584vs0.445,0.579vs0.528,P<0.01)。对于两种性别的低肌肉质量，ROC分析更青睐PVMQ而不是VBQ（AUC=0.767vs0.718，0.793vs0.718）。VBQ对男性骨量较好（0.737/0.865vs0.691/0.858），而PVMQ在女性中表现优异（0.808/0.764vs0.721/0.718）。
■新的PVMQ评分对椎旁肌肉质量提供了可靠的评估，并显示出与VBQ评分和DFF的强相关性，尤其是女性。它在评估肌肉质量方面优于VBQ评分，并为评估女性骨骼质量提供了有价值的见解。这些发现强调了PVMQ评分作为评估肌肉和骨骼健康的双重目的工具的潜力。为未来的研究和临床实践提供信息。
