UNASSIGNED: We conducted a cross-sectional study between January and April 2021 in Bamako and Kati regions to evaluate both rapid tests during a large SARS-CoV-2 prevalence study in Mali.
UNASSIGNED: Of the 390 samples tested, the sensitivity and specificity of Realy Tech™ and Standard Q™ were 57.1% (95%CI: 44.1-69.2), 95.8% (95%CI: 93.1-97.5); 61.9% (95%CI: 46.8-75.0), and 94.1% (95%CI: 89.5-96.8) respectively. Using RT-PCR, the global prevalence of SARS-CoV-2 was 14.4% (56/390). In both rapid antigen tests, the performance was better when used in suspected patients compared to positive patients under treatment. Moreover, higher viral loads equivalent to Ct < 25 were associated with better detection rates.
UNASSIGNED: While waiting for more complete data, these preliminary studies suggest that Realy Tech™ and Standard Q™ should not be used alone for COVID-19 diagnosis in Mali.
■我们在2021年1月至4月之间在巴马科和卡蒂地区进行了一项横断面研究,以评估在马里进行的大型SARS-CoV-2流行研究中的两种快速测试。
■在测试的390个样品中,RealyTech™和StandardQ™的敏感性和特异性为57.1%(95CI:44.1-69.2),95.8%(95CI:93.1-97.5);61.9%(95CI:46.8-75.0),和94.1%(95CI:89.5-96.8)。使用RT-PCR,SARS-CoV-2的全球患病率为14.4%(56/390)。在两种快速抗原测试中,与接受治疗的阳性患者相比,在疑似患者中使用时的表现更好.此外,相当于Ct<25的较高病毒载量与较好的检出率相关.
■在等待更完整的数据时,这些初步研究表明,RealyTech™和StandardQ™不应单独用于马里的COVID-19诊断。