CONCLUSIONS: Future research should build on these findings by emphasizing ongoing efforts to combat MRSA in pediatric settings and implementing targeted interventions.
BACKGROUND: • Methicillin-resistant Staphylococcus aureus (MRSA) is considered a threat to public health. It is noteworthy to mention that the prevalence of MRSA strains has not been adequately quantified in many countries, especially in the pediatric population. The pediatric population is a pivotal source of MRSA and may play a central role in its distribution in both community and healthcare settings. A notable study underscores the gravity of the situation, estimating a tenfold increase in the incidence of MRSA infection among children in the USA between 1999 and 2008.
BACKGROUND: • Here we present the first global systematic review and meta-analysis to investigate the prevalence and risk factors of MRSA among the pediatric population. A total of 124 studies encompassing 44 million participants were included in this analysis. The overall pooled estimated global prevalence of MRSA colonization in the pediatric population was 5% [95% CI 4-5%]. The prevalence was the highest in Asia and lowest in Europe. Female sex, recent surgery, recent hospitalization, and antibiotic use were significantly associated with higher odds of MRSA colonization.
结论:未来的研究应以这些发现为基础,强调在儿科环境中持续努力对抗MRSA并实施有针对性的干预措施。
背景:•耐甲氧西林金黄色葡萄球菌(MRSA)被认为是对公共卫生的威胁。值得注意的是,MRSA菌株的流行在许多国家还没有得到充分的量化,尤其是在儿科人群中。儿科人群是MRSA的关键来源,可能在社区和医疗机构中的分布中起着核心作用。一项值得注意的研究强调了局势的严重性,估计1999年至2008年间,美国儿童MRSA感染的发病率增加了10倍。
背景:在这里,我们首次进行全球系统综述和荟萃分析,以调查MRSA在儿科人群中的患病率和危险因素。共有124项研究,包括4400万参与者。儿科人群中MRSA定植的总体汇总估计全球患病率为5%[95%CI4-5%]。患病率在亚洲最高,在欧洲最低。女性性别,最近的手术,最近住院,抗生素的使用与MRSA定植几率较高显著相关.