PDF(Pubmed)
Abstract：
UNASSIGNED: Egocentric and allocentric spatial memory impairments affect the navigation abilities of older adults with mild cognitive impairment (MCI). Embodied cognition research hints that specific aids can be implemented into virtual reality (VR) training to enhance spatial memory.
UNASSIGNED: In this study, we preliminarily tested \'ANTaging\', an embodied-based immersive VR training for egocentric and allocentric memory, compared to treatment as usual (TAU) spatial training in MCI.
UNASSIGNED: MCI patients were recruited for this controlled trial. A cognitive battery was administered at pre-test, after ten sessions of ANTaging or TAU intervention, and at 3-month follow-up (FU). The primary outcomes were spatial cognition tests (Corsi supra-span, CSS; Manikin test, MT). VR egocentric and allocentric performance was also collected.
UNASSIGNED: We found that ANTaging significantly improved MT scores at FU compared to TAU. CSS slightly improved in both groups. Concerning secondary outcomes, auditory-verbal forgetting significantly improved at post-test in the ANTaging but not TAU group and significantly declined at FU in the TAU but not in the ANTaging group. Global cognition significantly improved at FU for TAU and remained stable for ANTaging. Other tests showed no improvement or deterioration. Clinical significance showed that ANTaging is effective for CSS. Virtual egocentric and allocentric memory performance improved across ANTaging sessions.
UNASSIGNED: ANTaging holds the potential to be superior for improving spatial cognition in MCI compared to TAU. Embodied cognition research provides insights for designing effective spatial navigation rehabilitation in aging.
UNASSIGNED: In this study, we preliminarily tested \'ANTaging\', an embodied-based immersive VR training for egocentric and allocentric memory, compared to treatment as usual (TAU) spatial training in MCI.
UNASSIGNED: MCI patients were recruited for this controlled trial. A cognitive battery was administered at pre-test, after ten sessions of ANTaging or TAU intervention, and at 3-month follow-up (FU). The primary outcomes were spatial cognition tests (Corsi supra-span, CSS; Manikin test, MT). VR egocentric and allocentric performance was also collected.
UNASSIGNED: We found that ANTaging significantly improved MT scores at FU compared to TAU. CSS slightly improved in both groups. Concerning secondary outcomes, auditory-verbal forgetting significantly improved at post-test in the ANTaging but not TAU group and significantly declined at FU in the TAU but not in the ANTaging group. Global cognition significantly improved at FU for TAU and remained stable for ANTaging. Other tests showed no improvement or deterioration. Clinical significance showed that ANTaging is effective for CSS. Virtual egocentric and allocentric memory performance improved across ANTaging sessions.
UNASSIGNED: ANTaging holds the potential to be superior for improving spatial cognition in MCI compared to TAU. Embodied cognition research provides insights for designing effective spatial navigation rehabilitation in aging.
摘要：
■以自我为中心和以分配为中心的空间记忆障碍会影响患有轻度认知障碍（MCI）的老年人的导航能力。具体认知研究暗示可以将特定的辅助工具实施到虚拟现实（VR）训练中以增强空间记忆。
■在这项研究中，我们初步测试了\'ANTaging\'，一种以自我为中心和以分配为中心的沉浸式VR训练，与MCI中照常治疗(TAU)空间训练相比。
■这项对照试验招募了MCI患者。在预测测试中使用了认知电池，经过十次ANTaging或TAU干预后，3个月随访（FU）。主要结果是空间认知测试(Corsisupra-span，CSS;人体模型测试,MT）。还收集了以自我为中心和以分配为中心的VR性能。
■我们发现，与TAU相比，ANTaging显着提高了FU的MT得分。CSS在两组中略有改善。关于次要结果，在ANTaging而不是TAU组中，听觉-言语遗忘在测试后显着改善，而在TAU中，在FU中显着下降，但在ANTaging组中没有。对于TAU，FU的全球认知显着改善，对于ANTaging保持稳定。其他测试显示没有改善或恶化。临床意义表明ANTaging对CSS有效。在ANTaging会话中，虚拟以自我为中心和以分配为中心的内存性能得到了改进。
■与TAU相比，ANTaging具有改善MCI空间认知的潜力。具身认知研究为设计有效的空间导航康复提供了见解。
■在这项研究中，我们初步测试了\'ANTaging\'，一种以自我为中心和以分配为中心的沉浸式VR训练，与MCI中照常治疗(TAU)空间训练相比。
■这项对照试验招募了MCI患者。在预测测试中使用了认知电池，经过十次ANTaging或TAU干预后，3个月随访（FU）。主要结果是空间认知测试(Corsisupra-span，CSS;人体模型测试,MT）。还收集了以自我为中心和以分配为中心的VR性能。
■我们发现，与TAU相比，ANTaging显着提高了FU的MT得分。CSS在两组中略有改善。关于次要结果，在ANTaging而不是TAU组中，听觉-言语遗忘在测试后显着改善，而在TAU中，在FU中显着下降，但在ANTaging组中没有。对于TAU，FU的全球认知显着改善，对于ANTaging保持稳定。其他测试显示没有改善或恶化。临床意义表明ANTaging对CSS有效。在ANTaging会话中，虚拟以自我为中心和以分配为中心的内存性能得到了改进。
■与TAU相比，ANTaging具有改善MCI空间认知的潜力。具身认知研究为设计有效的空间导航康复提供了见解。
