Abstract：
UNASSIGNED: The historical focus of vaccines on child health coupled with the advent of novel vaccines targeting adult populations necessitates exploring strategies for adult vaccine implementation.
UNASSIGNED: This scoping review extracts insights from the past decade\'s experiences introducing adult vaccines in low- and middle-income countries. Among 25 papers reviewed, 19 focused on oral cholera vaccine, 2 on Meningococcal A vaccines, 2 on tetanus toxoid vaccine, 1 on typhoid vaccine, and 1 on Ebola vaccine. Aligned with WHO\'s Global Framework for New TB Vaccines for Adults and Adolescents, our findings center on vaccine availability, accessibility, and acceptance.
UNASSIGNED: Availability findings underscore the importance of understanding disease burden for prioritization, multi-sectoral collaboration during planning, and strategic resource allocation and coordination. Accessibility results highlight the benefits of leveraging existing health infrastructure and adequately training healthcare workers, and contextually tailoring vaccine delivery approaches to reach challenging sub-groups like working male adults. Central to fostering acceptance, resonant sensitization, and communication campaigns engaging the communities and utilizing trusted local leaders countered rumors and increased awareness and uptake. As we approach the introduction of a new adult TB vaccine, insights from this review equips decision-makers with key evidence-based recommendations to support successful and equitable vaccinations targeting adults.
UNASSIGNED: This scoping review extracts insights from the past decade\'s experiences introducing adult vaccines in low- and middle-income countries. Among 25 papers reviewed, 19 focused on oral cholera vaccine, 2 on Meningococcal A vaccines, 2 on tetanus toxoid vaccine, 1 on typhoid vaccine, and 1 on Ebola vaccine. Aligned with WHO\'s Global Framework for New TB Vaccines for Adults and Adolescents, our findings center on vaccine availability, accessibility, and acceptance.
UNASSIGNED: Availability findings underscore the importance of understanding disease burden for prioritization, multi-sectoral collaboration during planning, and strategic resource allocation and coordination. Accessibility results highlight the benefits of leveraging existing health infrastructure and adequately training healthcare workers, and contextually tailoring vaccine delivery approaches to reach challenging sub-groups like working male adults. Central to fostering acceptance, resonant sensitization, and communication campaigns engaging the communities and utilizing trusted local leaders countered rumors and increased awareness and uptake. As we approach the introduction of a new adult TB vaccine, insights from this review equips decision-makers with key evidence-based recommendations to support successful and equitable vaccinations targeting adults.
摘要：
疫苗对儿童健康的历史关注，加上针对成人人群的新型疫苗的出现，有必要探索成人疫苗实施的策略。
■本范围审查从过去十年在低收入和中等收入国家引入成人疫苗的经验中提取了一些见解。在25篇论文中，19专注于口服霍乱疫苗，2关于脑膜炎球菌A疫苗，2破伤风类毒素疫苗，伤寒疫苗1，和1埃博拉疫苗。与世界卫生组织的成人和青少年新型结核病疫苗全球框架保持一致，我们的发现集中在疫苗的可用性，可访问性,和接受。
■可用性调查结果强调了了解疾病负担对优先排序的重要性，规划期间的多部门合作，和战略资源分配与协调。可访问性结果突出了利用现有卫生基础设施和充分培训医护人员的好处。和上下文定制疫苗输送方法，以达到具有挑战性的亚组，如工作的男性成年人。促进接受的核心，共鸣的宣传和宣传活动，让社区参与进来，利用值得信赖的地方领导人，抵制谣言，提高人们的认识和吸收。随着我们即将推出一种新的成人结核病疫苗，本综述的见解为决策者提供了关键的循证建议,以支持针对成年人的成功和公平的疫苗接种.
■本范围审查从过去十年在低收入和中等收入国家引入成人疫苗的经验中提取了一些见解。在25篇论文中，19专注于口服霍乱疫苗，2关于脑膜炎球菌A疫苗，2破伤风类毒素疫苗，伤寒疫苗1，和1埃博拉疫苗。与世界卫生组织的成人和青少年新型结核病疫苗全球框架保持一致，我们的发现集中在疫苗的可用性，可访问性,和接受。
■可用性调查结果强调了了解疾病负担对优先排序的重要性，规划期间的多部门合作，和战略资源分配与协调。可访问性结果突出了利用现有卫生基础设施和充分培训医护人员的好处。和上下文定制疫苗输送方法，以达到具有挑战性的亚组，如工作的男性成年人。促进接受的核心，共鸣的宣传和宣传活动，让社区参与进来，利用值得信赖的地方领导人，抵制谣言，提高人们的认识和吸收。随着我们即将推出一种新的成人结核病疫苗，本综述的见解为决策者提供了关键的循证建议,以支持针对成年人的成功和公平的疫苗接种.
