PDF(Pubmed)
Abstract：
OBJECTIVE: Estimating the number of deaths caused by smoking is crucial for developing and evaluating tobacco control and smoking cessation policies. This study aimed to determine smoking-attributable mortality (SAM) in Korea in 2020.
METHODS: Four large-scale cohorts from Korea were analyzed. A Cox proportional-hazards model was used to determine the hazard ratios (HRs) of smoking-related death. By conducting a meta-analysis of these HRs, the pooled HRs of smoking-related death for 41 diseases were estimated. Population-attributable fractions (PAFs) were calculated based on the smoking prevalence for 1995 in conjunction with the pooled HRs. Subsequently, SAM was derived using the PAF and the number of deaths recorded for each disease in 2020.
RESULTS: The pooled HR for all-cause mortality attributable to smoking was 1.73 for current men smokers (95% confidence interval [CI], 1.53 to 1.95) and 1.63 for current women smokers (95% CI, 1.37 to 1.94). Smoking accounted for 33.2% of all-cause deaths in men and 4.6% in women. Additionally, it was a factor in 71.8% of men lung cancer deaths and 11.9% of women lung cancer deaths. In 2020, smoking was responsible for 53 930 men deaths and 6283 women deaths, totaling 60 213 deaths.
CONCLUSIONS: Cigarette smoking was responsible for a significant number of deaths in Korea in 2020. Monitoring the impact and societal burden of smoking is essential for effective tobacco control and harm prevention policies.
METHODS: Four large-scale cohorts from Korea were analyzed. A Cox proportional-hazards model was used to determine the hazard ratios (HRs) of smoking-related death. By conducting a meta-analysis of these HRs, the pooled HRs of smoking-related death for 41 diseases were estimated. Population-attributable fractions (PAFs) were calculated based on the smoking prevalence for 1995 in conjunction with the pooled HRs. Subsequently, SAM was derived using the PAF and the number of deaths recorded for each disease in 2020.
RESULTS: The pooled HR for all-cause mortality attributable to smoking was 1.73 for current men smokers (95% confidence interval [CI], 1.53 to 1.95) and 1.63 for current women smokers (95% CI, 1.37 to 1.94). Smoking accounted for 33.2% of all-cause deaths in men and 4.6% in women. Additionally, it was a factor in 71.8% of men lung cancer deaths and 11.9% of women lung cancer deaths. In 2020, smoking was responsible for 53 930 men deaths and 6283 women deaths, totaling 60 213 deaths.
CONCLUSIONS: Cigarette smoking was responsible for a significant number of deaths in Korea in 2020. Monitoring the impact and societal burden of smoking is essential for effective tobacco control and harm prevention policies.
摘要：
■估计吸烟导致的死亡人数对于制定和评估烟草控制和戒烟政策至关重要。这项研究旨在确定2020年韩国的吸烟归因死亡率（SAM）。
■分析了来自韩国的四个大规模队列。Cox比例风险模型用于确定吸烟相关死亡的风险比（HR）。通过对这些HR进行荟萃分析，对41种疾病的吸烟相关死亡的合并HR进行了估算.人口归因分数（PAF）是根据1995年的吸烟率和汇总的HR计算的。随后，SAM是使用PAF和2020年每种疾病记录的死亡人数得出的。
■当前男性吸烟者可归因于吸烟的全因死亡率的汇总HR为1.73（95％CI，1.532-1.954），当前女性吸烟者为1.531（95％CI，1.371-1.94）。吸烟占男性全因死亡的33.2%，女性占4.6%。此外,它是71.8%的男性肺癌死亡和11.9%的女性肺癌死亡的一个因素.在2020年，吸烟导致53,930名男性死亡和6,283名女性死亡。共60,213人死亡。
■吸烟是2020年韩国大量死亡的原因。监测吸烟的影响和社会负担对于有效的烟草控制和危害预防政策至关重要。
■分析了来自韩国的四个大规模队列。Cox比例风险模型用于确定吸烟相关死亡的风险比（HR）。通过对这些HR进行荟萃分析，对41种疾病的吸烟相关死亡的合并HR进行了估算.人口归因分数（PAF）是根据1995年的吸烟率和汇总的HR计算的。随后，SAM是使用PAF和2020年每种疾病记录的死亡人数得出的。
■当前男性吸烟者可归因于吸烟的全因死亡率的汇总HR为1.73（95％CI，1.532-1.954），当前女性吸烟者为1.531（95％CI，1.371-1.94）。吸烟占男性全因死亡的33.2%，女性占4.6%。此外,它是71.8%的男性肺癌死亡和11.9%的女性肺癌死亡的一个因素.在2020年，吸烟导致53,930名男性死亡和6,283名女性死亡。共60,213人死亡。
■吸烟是2020年韩国大量死亡的原因。监测吸烟的影响和社会负担对于有效的烟草控制和危害预防政策至关重要。
