关键词: Salmonella spp. Antibiotics Multidrug-resistant Tadla plain Water

Mesh : Morocco Salmonella / drug effects isolation & purification Anti-Bacterial Agents / pharmacology Groundwater / microbiology Humans Water Microbiology Microbial Sensitivity Tests Incidence Water Wells Drug Resistance, Bacterial Drug Resistance, Multiple, Bacterial

来  源:   DOI:10.1038/s41598-024-61917-3   PDF(Pubmed)

Abstract:
Concerns about challenges with water availability in the Tadla Plain region of Morocco have grown as a result of groundwater contamination brought on by human activity, climate change, and insufficient groundwater management. The objective of the study is to measure the number of resistant bacteria in the groundwater of Beni Moussa and Beni Aamir, as well as to evaluate the level of water pollution in this area. 200 samples were therefore gathered from 43 wells over the course of four seasonal campaigns in 2017 and 2018. Additionally, the samples were examined to determine whether Salmonella species were present and if they were resistant to the 16 antibiotics that were tested. Salmonella spp. have been identified in 31 isolated strains in total, accounting for 18.02% of all isolated strains. Data on antibiotic resistance show that 58.1% of Salmonella spp. strains are multidrug-resistant (MDR); 38.7% of Salmonella strains are tolerant to at least six antibiotics, 19.4% to at least nine antibiotics, 9.7% to four to seven antibiotics, 6.5% to at least eleven antibiotics, and the remaining 3.2% to up to twelve antibiotics. A considerable level of resistance to cefepime (61.29%), imipenem (54.84%), ceftazidime (45.16%), ofloxacin (70.97%), and ertapenem (74.19%) was found in the data. Consequently, it is important to monitor and regulate the growth of MDR in order to prevent the groundwater\'s quality from declining.
摘要:
由于人类活动造成的地下水污染,人们对摩洛哥塔德拉平原地区水资源供应面临的挑战感到担忧,气候变化,地下水管理不足。这项研究的目的是测量贝尼·穆萨和贝尼·阿米尔的地下水中耐药细菌的数量,以及评估该地区的水污染水平。因此,在2017年和2018年的四次季节性活动中,从43口井中收集了200个样本。此外,对样本进行检查,以确定是否存在沙门氏菌,以及它们是否对所测试的16种抗生素具有抗性。沙门氏菌属。已在总共31个分离菌株中鉴定出,占全部分离菌株的18.02%。抗生素耐药性数据显示,58.1%的沙门氏菌属。菌株具有多重耐药性(MDR);38.7%的沙门氏菌菌株对至少6种抗生素具有耐受性,19.4%到至少九种抗生素,9.7%至4至7种抗生素,6.5%至至少11种抗生素,其余3.2%至最多12种抗生素。对头孢吡肟的抗性相当高(61.29%),亚胺培南(54.84%),头孢他啶(45.16%),氧氟沙星(70.97%),数据中发现了厄他培南(74.19%)。因此,监测和调节MDR的增长对防止地下水质量下降具有重要意义。
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