Abstract：
OBJECTIVE: The ESPEN and the EASO recently developed consensus criteria for sarcopenic obesity (SO), employing the skeletal muscle mass to weight (SMM/W) ratio. Emerging evidence suggests that adjusting skeletal muscle mass for body mass index (SMM/BMI) could enhance the predictive accuracy for health outcomes. We aimed to validate the ESPEN/EASO criteria and explore the potential benefits of the SMM/BMI adjustment in predicting falls among older adults in Western China.
METHODS: We conducted a multicenter, cross-sectional study and included community-dwelling older adults. The diagnosis of SO was determined using the standard ESPEN/EASO consensus criteria (SOESPEN) and a modified version adjusting SMM/BMI (SOESPEN-M). The associations of SOESPEN, SOESPEN-M, and their components with falls were analyzed.
RESULTS: Among the 1353 participants, the prevalence of SO was 13.2 % (SOESPEN) and 11.4 % (SOESPEN-M), which increased with age and higher BMI levels. Within participants with a normal BMI, 4.2 % and 6.2 % were found to have SOESPEN and SOESPEN-M, respectively. SMM/W and SMM/BMI negatively correlated with fall risk (p=0.042 and p=0.021, respectively). Upon adjusting for confounders, only SOESPEN was significantly associated with falls (odds ratios [OR] 1.61, 95 % confidence interval [CI] 1.08 to 2.40), whereas the association for SOESPEN-M did not achieve significance (OR 1.55, 95 % CI 0.99 to 2.43).
CONCLUSIONS: This research validated the ESPEN/EASO criteria (SOESPEN) and their modified version (SOESPEN-M) among community-dwelling older adults in Western China. The SMM/BMI adjustment appears to offer a lower estimate of SO prevalence, with only SOESPEN showing a significant association with falls.
METHODS: We conducted a multicenter, cross-sectional study and included community-dwelling older adults. The diagnosis of SO was determined using the standard ESPEN/EASO consensus criteria (SOESPEN) and a modified version adjusting SMM/BMI (SOESPEN-M). The associations of SOESPEN, SOESPEN-M, and their components with falls were analyzed.
RESULTS: Among the 1353 participants, the prevalence of SO was 13.2 % (SOESPEN) and 11.4 % (SOESPEN-M), which increased with age and higher BMI levels. Within participants with a normal BMI, 4.2 % and 6.2 % were found to have SOESPEN and SOESPEN-M, respectively. SMM/W and SMM/BMI negatively correlated with fall risk (p=0.042 and p=0.021, respectively). Upon adjusting for confounders, only SOESPEN was significantly associated with falls (odds ratios [OR] 1.61, 95 % confidence interval [CI] 1.08 to 2.40), whereas the association for SOESPEN-M did not achieve significance (OR 1.55, 95 % CI 0.99 to 2.43).
CONCLUSIONS: This research validated the ESPEN/EASO criteria (SOESPEN) and their modified version (SOESPEN-M) among community-dwelling older adults in Western China. The SMM/BMI adjustment appears to offer a lower estimate of SO prevalence, with only SOESPEN showing a significant association with falls.
摘要：
目的：ESPEN和EASO最近制定了关于节育性肥胖（SO）的共识标准，采用骨骼肌质量与重量(SMM/W)的比率。新的证据表明，根据体重指数（SMM/BMI）调整骨骼肌质量可以提高健康结果的预测准确性。我们旨在验证ESPEN/EASO标准，并探讨SMM/BMI调整在预测中国西部老年人跌倒中的潜在益处。
方法：我们进行了多中心，横断面研究，包括社区居住的老年人。使用标准的ESPEN/EASO共识标准（SOESPEN）和调整SMM/BMI的修改版本（SOESPEN-M）确定SO的诊断。SOESPEN协会，SOESPEN-M,并分析了它们与跌倒的成分。
结果：在1353名参与者中，SO的患病率为13.2%(SOESPEN)和11.4%(SOESPEN-M)，随着年龄和较高的BMI水平而增加。在BMI正常的参与者中，4.2%和6.2%被发现有SOESPEN和SOESPEN-M，分别。SMM/W和SMM/BMI与跌倒风险呈负相关(分别为p=0.042和p=0.021)。在调整混杂因素后，只有SOESPEN与跌倒显着相关（优势比[OR]1.61，95％置信区间[CI]1.08至2.40），而SOESPEN-M的关联没有达到显著性(OR1.55,95%CI0.99~2.43).
结论：这项研究在中国西部社区居住的老年人中验证了ESPEN/EASO标准（SOESPEN）及其修改版本（SOESPEN-M）。SMM/BMI调整似乎提供了对SO患病率的较低估计，只有SOESPEN显示与跌倒有显著关联。
方法：我们进行了多中心，横断面研究，包括社区居住的老年人。使用标准的ESPEN/EASO共识标准（SOESPEN）和调整SMM/BMI的修改版本（SOESPEN-M）确定SO的诊断。SOESPEN协会，SOESPEN-M,并分析了它们与跌倒的成分。
结果：在1353名参与者中，SO的患病率为13.2%(SOESPEN)和11.4%(SOESPEN-M)，随着年龄和较高的BMI水平而增加。在BMI正常的参与者中，4.2%和6.2%被发现有SOESPEN和SOESPEN-M，分别。SMM/W和SMM/BMI与跌倒风险呈负相关(分别为p=0.042和p=0.021)。在调整混杂因素后，只有SOESPEN与跌倒显着相关（优势比[OR]1.61，95％置信区间[CI]1.08至2.40），而SOESPEN-M的关联没有达到显著性(OR1.55,95%CI0.99~2.43).
结论：这项研究在中国西部社区居住的老年人中验证了ESPEN/EASO标准（SOESPEN）及其修改版本（SOESPEN-M）。SMM/BMI调整似乎提供了对SO患病率的较低估计，只有SOESPEN显示与跌倒有显著关联。
