关键词: bionic synapse chemical tunability nanofluidic potential spiking transmembrane

Mesh : Action Potentials / physiology Synapses / physiology Polystyrenes / chemistry Nanotechnology / methods instrumentation

来  源:   DOI:10.1073/pnas.2403143121

Abstract:
Currently, the nanofluidic synapse can only perform basic neuromorphic pulse patterns. One immediate problem that needs to be addressed to further its capability of brain-like computing is the realization of a nanofluidic spiking device. Here, we report the use of a poly(3,4-ethylenedioxythiophene) polystyrene sulfonate membrane to achieve bionic ionic current-induced spiking. In addition to the simulation of various electrical pulse patterns, our synapse could produce transmembrane ionic current-induced spiking, which is highly analogous to biological action potentials with similar phases and excitability. Moreover, the spiking properties could be modulated by ions and neurochemicals. We expect that this work could contribute to biomimetic spiking computing in solution.
摘要:
目前,纳米流体突触只能执行基本的神经形态脉冲模式。需要解决的一个直接问题是实现纳米流体尖峰设备,以进一步增强其类似大脑的计算能力。这里,我们报告了使用聚(3,4-亚乙基二氧噻吩)聚苯乙烯磺酸盐膜来实现仿生离子电流诱导的加标。除了模拟各种电脉冲模式,我们的突触可以产生跨膜离子电流诱导的尖峰,这与具有相似阶段和兴奋性的生物动作电位高度相似。此外,尖峰特性可以通过离子和神经化学物质来调节。我们希望这项工作可以为解决方案中的仿生尖峰计算做出贡献。
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