PDF(Pubmed)
Abstract：
UNASSIGNED: Spontaneous preterm delivery is defined as the beginning of the birth process before the 37th week of pregnancy. The presence of microorganisms in the fetal membranes is accompanied by an increase in the production of prostaglandin, one of the important factors associated with the prevalence of preterm birth. The invasion of microorganisms leads to the production of protease, coagulase, and elastase, which directly stimulate the onset of childbirth. We investigated the role of genital infections in women with preterm birth.
UNASSIGNED: The present case-control study was conducted in the west of Iran on 100 women with spontaneous preterm delivery (following 24 weeks of gestation and before 36 weeks and 6 days) as the case group and 100 women with normal delivery as controls. A questionnaire was applied to collect the data. Polymerase chain reaction and pathological examination of the placenta were performed.
UNASSIGNED: The average age in women with normal delivery (30.92 ± 5.10) in women with spontaneous preterm delivery (30.27 ± 4.93). The prevalence of Chlamydia trachomatis, Neisseria gonorrhea, Listeria monocytogenes, and Mycoplasma genitalium infections was zero in both groups. The highest prevalence of Gardnerella vaginalis was 19 (19%) in the case group and Ureaplasma parvum 15 (15%) in the control group. Also, Placental inflammation was zero in controls and 7(7%) in the patient group. There was a significant relationship between Gardnerella vaginalis bacteria and spontaneous preterm delivery.
UNASSIGNED: The results of our study showed that except for Gardnerella vaginalis bacteria, there is no significant relationship between the above bacterial infections and spontaneous preterm birth. Moreover, despite the significant reduction in the prevalence of many sexually transmitted infections in this research, it is still suggested to increase the awareness of people, including pregnant women, about the ways it can be transmitted by gynecologists and health and treatment centers.
UNASSIGNED: The present case-control study was conducted in the west of Iran on 100 women with spontaneous preterm delivery (following 24 weeks of gestation and before 36 weeks and 6 days) as the case group and 100 women with normal delivery as controls. A questionnaire was applied to collect the data. Polymerase chain reaction and pathological examination of the placenta were performed.
UNASSIGNED: The average age in women with normal delivery (30.92 ± 5.10) in women with spontaneous preterm delivery (30.27 ± 4.93). The prevalence of Chlamydia trachomatis, Neisseria gonorrhea, Listeria monocytogenes, and Mycoplasma genitalium infections was zero in both groups. The highest prevalence of Gardnerella vaginalis was 19 (19%) in the case group and Ureaplasma parvum 15 (15%) in the control group. Also, Placental inflammation was zero in controls and 7(7%) in the patient group. There was a significant relationship between Gardnerella vaginalis bacteria and spontaneous preterm delivery.
UNASSIGNED: The results of our study showed that except for Gardnerella vaginalis bacteria, there is no significant relationship between the above bacterial infections and spontaneous preterm birth. Moreover, despite the significant reduction in the prevalence of many sexually transmitted infections in this research, it is still suggested to increase the awareness of people, including pregnant women, about the ways it can be transmitted by gynecologists and health and treatment centers.
摘要：
■自发性早产被定义为怀孕第37周之前出生过程的开始。胎膜中微生物的存在伴随着前列腺素产量的增加，与早产患病率相关的重要因素之一。微生物的入侵导致蛋白酶的产生，凝固酶,和弹性蛋白酶,这直接刺激了分娩的开始。我们调查了生殖器感染在早产妇女中的作用。
■本病例对照研究是在伊朗西部对100名自发性早产妇女（妊娠24周后和36周零6天之前）作为病例组进行的，100名正常分娩的妇女作为对照。采用问卷收集数据。对胎盘进行聚合酶链反应和病理检查。
■正常分娩妇女的平均年龄（30.92±5.10），自发性早产妇女（30.27±4.93）。沙眼衣原体的患病率，淋病奈瑟菌,单核细胞增生李斯特菌,两组生殖道支原体感染均为零。在病例组中，阴道加德纳菌的患病率最高，为19（19％），在对照组中为小脲原体15（15％）。此外，胎盘炎症在对照组中为零，在患者组中为7（7％）。阴道加德纳菌与自发性早产之间存在显着关系。
■我们的研究结果表明，除了阴道加德纳菌，上述细菌感染与自发性早产无明显关系。此外，尽管在这项研究中许多性传播感染的患病率显着降低，仍然建议提高人们的意识，包括孕妇,关于妇科医生和健康治疗中心传播它的方式。
■本病例对照研究是在伊朗西部对100名自发性早产妇女（妊娠24周后和36周零6天之前）作为病例组进行的，100名正常分娩的妇女作为对照。采用问卷收集数据。对胎盘进行聚合酶链反应和病理检查。
■正常分娩妇女的平均年龄（30.92±5.10），自发性早产妇女（30.27±4.93）。沙眼衣原体的患病率，淋病奈瑟菌,单核细胞增生李斯特菌,两组生殖道支原体感染均为零。在病例组中，阴道加德纳菌的患病率最高，为19（19％），在对照组中为小脲原体15（15％）。此外，胎盘炎症在对照组中为零，在患者组中为7（7％）。阴道加德纳菌与自发性早产之间存在显着关系。
■我们的研究结果表明，除了阴道加德纳菌，上述细菌感染与自发性早产无明显关系。此外，尽管在这项研究中许多性传播感染的患病率显着降低，仍然建议提高人们的意识，包括孕妇,关于妇科医生和健康治疗中心传播它的方式。
