Abstract：
The work presents the connection between the infection of COVID-19 during pregnancy and non-syndromic orofacial clefts (NSOFC). Aim of the study was to compare the incidence of COVID-19 disease during mother´s pregnancy between a group of the children with NSOFC and a control group of the children without NSOFC. COVID-19 was confirmed by polymerase chain reaction (PCR) test. The study showed significantly higher incidence of COVID-19 disease in the group of mothers who gave birth to a child with NSOFC in comparison to the group of mothers who gave birth to a child without NSOFC. Our results indicate the possible participation of the infection of COVID-19 in the formation of NSOFCs.
摘要：
这项工作提出了怀孕期间COVID-19感染与非综合征性口面裂痕（NSOFC）之间的联系。这项研究的目的是比较一组患有NSOFC的儿童和没有NSOFC的儿童的对照组在母亲怀孕期间COVID-19疾病的发病率。COVID-19通过聚合酶链反应(PCR)检测得到证实。研究表明，与没有NSOFC的孩子的母亲组相比，生下NSOFC孩子的母亲组的COVID-19疾病发病率明显更高。我们的结果表明，COVID-19的感染可能参与了NSOFC的形成。
