%0 Journal Article
%T Relationship between COVID-19 and orofacial clefts.
%A Molnárová A
%A Fekiačová D
%A Záhumenský J
%A Rosoľanková M
%A Ujházy E
%A Dubovický M
%A Palenčár D
%J Gen Physiol Biophys
%V 43
%N 4
%D 2024 Jul
%M 38953573
%F 1.957
%R 10.4149/gpb_2024012
%X The work presents the connection between the infection of COVID-19 during pregnancy and non-syndromic orofacial clefts (NSOFC). Aim of the study was to compare the incidence of COVID-19 disease during mother´s pregnancy between a group of the children with NSOFC and a control group of the children without NSOFC. COVID-19 was confirmed by polymerase chain reaction (PCR) test. The study showed significantly higher incidence of COVID-19 disease in the group of mothers who gave birth to a child with NSOFC in comparison to the group of mothers who gave birth to a child without NSOFC. Our results indicate the possible participation of the infection of COVID-19 in the formation of NSOFCs.